Western Blot (WB)
(Western Blot analysis of TRAF2 expression in transfected 293T cell line by TRAF2 monoclonal antibody. Lane 1: TRAF2 transfected lysate (55.9kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human TRAF2 Monoclonal Antibody | anti-TRAF2 antibody
TRAF2 (TNF Receptor-associated Factor 2, E3 Ubiquitin-protein Ligase TRAF2, Tumor Necrosis Factor Type 2 Receptor-associated Protein 3, TRAP3, MGC:45012) (Biotin)
Western Blot (WB)
(Western Blot analysis of TRAF2 expression in transfected 293T cell line by TRAF2 monoclonal antibody. Lane 1: TRAF2 transfected lysate (55.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of TRAF2 expression in transfected 293T cell line by TRAF2 monoclonal antibody. Lane 1: TRAF2 transfected lysate (55.9kD). Lane 2: Non-transfected lysate.)
Testing Data
(Proximity Ligation Analysis of protein-protein interactions between IKBKB and TRAF2 HeLa cells were stained with IKBKB rabbit purified polyclonal 1:1200 and TRAF2 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).)
Testing Data
(Proximity Ligation Analysis of protein-protein interactions between IKBKB and TRAF2 HeLa cells were stained with IKBKB rabbit purified polyclonal 1:1200 and TRAF2 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined. [provided by RefSeq, Jul 2008]
Research Articles on TRAF2
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Product Notes
The TRAF2 (Catalog #AAA6144898) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TRAF2 (TNF Receptor-associated Factor 2, E3 Ubiquitin-protein Ligase TRAF2, Tumor Necrosis Factor Type 2 Receptor-associated Protein 3, TRAP3, MGC:45012) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRAF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TRAF2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRAF2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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