Testing Data
(Detection limit for recombinant GST tagged TNRC6B is 0.3 ng/ml as a capture antibody.)
Mouse TNRC6B Monoclonal Antibody | anti-TNRC6B antibody
TNRC6B (trinucleotide Repeat Containing 6B, KIAA1093) (AP)
Testing Data
(Detection limit for recombinant GST tagged TNRC6B is 0.3 ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged TNRC6B is 0.3 ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
Uniprot Description
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. Ref.7 Ref.10 Ref.11 Ref.16
Subunit structure: Interacts with AGO1, AGO2, AGO3 and AGO4. Interacts with CNOT1; the interaction mediates the association with the CCR4-NOT complex. Interacts with PAN3; the interaction mediates the association with the PAN complex. Ref.7 Ref.8 Ref.10 Ref.11 Ref.12 Ref.16 Ref.17
Subcellular location: Cytoplasm › P-body. Note: Mammalian P-bodies are also known as GW bodies (GWBs). Ref.7 Ref.10
Sequence similarities: Belongs to the GW182 family.Contains 1 RRM (RNA recognition motif) domain.
Sequence caution: The sequence BAA83045.2 differs from that shown. Reason: Erroneous initiation.
Research Articles on TNRC6B
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Product Notes
The TNRC6B tnrc6b (Catalog #AAA6164462) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TNRC6B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TNRC6B tnrc6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNRC6B, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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