IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using OTULIN Polyclonal Antibody at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.)
Rabbit OTULIN Polyclonal Antibody | anti-OTULIN antibody
OTULIN Polyclonal Antibody
Gene Names
OTULIN; GUM; FAM105B
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
OTULIN, Antibody; OTULIN Polyclonal Antibody; GUM; AIPDS; FAM105B; anti-OTULIN antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-OTULIN antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human OTULIN
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using OTULIN Polyclonal Antibody at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using OTULIN Polyclonal Antibody at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.)
WB (Western Blot)
(Western blot analysis of extracts of MCF7 cells using OTULIN Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of MCF7 cells using OTULIN Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of Rat liver using OTULIN Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of Rat liver using OTULIN Polyclonal Antibody at 1:1000 dilution.)
Related Product Information for anti-OTULIN antibody
This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients.
Product Categories/Family for anti-OTULIN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,263 Da
NCBI Official Full Name
ubiquitin thioesterase otulin
NCBI Official Synonym Full Names
OTU deubiquitinase with linear linkage specificity
NCBI Official Symbol
OTULIN
NCBI Official Synonym Symbols
GUM; FAM105B
NCBI Protein Information
ubiquitin thioesterase otulin; gumby; protein FAM105B; ubiquitin thioesterase Gumby; deubiquitinating enzyme otulin; family with sequence similarity 105, member B; OTU domain-containing deubiquitinase with linear linkage specificity
UniProt Protein Name
Ubiquitin thioesterase otulin
UniProt Gene Name
OTULIN
UniProt Synonym Gene Names
FAM105B
UniProt Entry Name
OTUL_HUMAN
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Product Notes
The OTULIN otulin (Catalog #AAA179287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OTULIN Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's OTULIN can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the OTULIN otulin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OTULIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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