Western Blot (WB)
(Western Blot analysis of Y79 cells using TELO2 Monoclonal Antibody at dilution of 1:2000)
Mouse anti-Human TELO2 Monoclonal Antibody | anti-TELO2 antibody
TELO2 Monoclonal Antibody
Gene Names
TELO2; CLK2; TEL2; YHFS
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Protein G purification
Synonyms
TELO2; Monoclonal Antibody; TELO2 Monoclonal Antibody; CLK2; hCLK2; KIAA0683; Protein clk-2 homolog; TEL2; TEL2 telomere maintenance 2 homolog; telomere maintenance 2; homolog; telo2; Telomere length regulation protein TEL2 homolog; Telomere maintenance 2; anti-TELO2 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
950
Purity/Purification
Protein G purification
Concentration
1mg/mL (varies by lot)
Sequence Length
837
Applicable Applications for anti-TELO2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:1000-1:10000
IHC: 1:20-1:200
IF: 1:10-1:100
IHC: 1:20-1:200
IF: 1:10-1:100
Immunogen
Fusion protein of TELO2
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western Blot analysis of Y79 cells using TELO2 Monoclonal Antibody at dilution of 1:2000)
Western Blot (WB)
(Western Blot analysis of Y79 cells using TELO2 Monoclonal Antibody at dilution of 1:2000)
Related Product Information for anti-TELO2 antibody
TELO2 gene encodes a telomere length regulation protein TEL2 homolog. TELO2 may be involved in telomere length regulation and can form TTT complex with TTI1 and TTI2. TTT complex is required to stabilize protein levels of PIKK family proteins and is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). The activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals, can be promoted, stabilized and maintained by TELO2.
Product Categories/Family for anti-TELO2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 92kDa
Observed: 92kDa
Observed: 92kDa
NCBI Official Full Name
telomere length regulation protein TEL2 homolog
NCBI Official Synonym Full Names
telomere maintenance 2
NCBI Official Symbol
TELO2
NCBI Official Synonym Symbols
CLK2; TEL2; YHFS
NCBI Protein Information
telomere length regulation protein TEL2 homolog
UniProt Protein Name
Telomere length regulation protein TEL2 homolog
Protein Family
UniProt Gene Name
TELO2
UniProt Synonym Gene Names
KIAA0683; hCLK2
NCBI Description
This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.[provided by RefSeq, Mar 2009]
Uniprot Description
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Research Articles on TELO2
Similar Products
Product Notes
The TELO2 telo2 (Catalog #AAA2542086) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The TELO2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TELO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:1000-1:10000 IHC: 1:20-1:200 IF: 1:10-1:100. Researchers should empirically determine the suitability of the TELO2 telo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TELO2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
