Hamster anti-Mouse TCR gamma/delta Monoclonal Antibody | anti-TCR gamma/delta antibody
Purified Anti-Mouse TCR gamma/delta Monoclonal Antibody
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay, Immunoprecipitation
Synonyms
TCR gamma/delta; Monoclonal Antibody; Purified Anti-Mouse TCR gamma/delta Monoclonal Antibody; TCR-gamma/delta; gamma/delta TCR; anti-TCR gamma/delta antibody
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
UC7-13D5
Form/Format
Liquid; PBS with 0.05% Proclin300
Applicable Applications for anti-TCR gamma/delta antibody
Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C. Do not freeze.
Related Product Information for anti-TCR gamma/delta antibody
T cell receptor (TCR) is a heterodimer consisting of an alpha and a beta chain (TCR alpha/beta) or a gamma and a delta chain (TCR gamma/delta). TCR gamma/delta belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR gamma/delta associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most gamma/delta T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR gamma/delta have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that gamma/delta T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-gamma/delta-bearing T cells in vitro, and to deplete peripheral TCR-gamma/delta-bearing T cells in vivo.
References
1. Skarstein K, et al. 1995. Immunology 81:497. 2. Harrison LC, et al. 1996. J. Exp. Med. 184:2167. 3. Wildner G, et al. 1996. Eur. J. Immunol. 26:2140. 4. Brandes M, et al. 2005. Science 309:264.
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Product Notes
The TCR gamma/delta (Catalog #AAA2556955) is an Antibody produced from Hamster and is intended for research purposes only. The product is available for immediate purchase. The Purified Anti-Mouse TCR gamma/delta Monoclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TCR gamma/delta can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the TCR gamma/delta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCR gamma/delta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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