Mouse TAF12 Monoclonal Antibody | anti-TAF12 antibody

Mouse monoclonal TAF12 antibody

Cat. Num. AAA5307457

• Gene Names: TAF12; TAF2J; TAFII20
• Applications: ELISA, Western Blot
• Synonyms: TAF12; Monoclonal Antibody; Mouse monoclonal TAF12 antibody; TAF12 antibody; anti-TAF12 antibody

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2b
• Clone Number: M78768
• Specificity: TAF12 antibody recognizes TAF12 expression in Hela whole cell lysate
• Form/Format: Supplied in citrate-tris-HCl buffer, pH 7.0 with 0.02% Proclin 300
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 161

• Applicable Applications for anti-TAF12 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: TAF12 antibody was raised in Mouse using a synthetic peptide (KLH-coupled) corresponding to the residues of TAF12 protein as the immunogen
• Preparation and Storage: Store at -20 degree C for 1 year, store at 2-8 degree C for up to 1 month.

Western Blot (WB)

(Western blot (1:500) analysis of TAF12 expression in Hela whole cell lysate with TAF12 antibody)

Product Categories/Family for anti-TAF12 antibody

DNA & RNA

NCBI and Uniprot Product Information

• NCBI GI #: 119628088
• NCBI GeneID: 6883
• Molecular Weight: 14,825 Da
• NCBI Official Full Name: TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa, isoform CRA_c
• NCBI Official Synonym Full Names: TATA-box binding protein associated factor 12
• NCBI Official Symbol: TAF12
• NCBI Official Synonym Symbols: TAF2J; TAFII20
• NCBI Protein Information: transcription initiation factor TFIID subunit 12
• UniProt Protein Name: Transcription initiation factor TFIID subunit 12
• Protein Family: Transcription initiation factor
• UniProt Gene Name: TAF12
• UniProt Synonym Gene Names: TAF15; TAF2J; TAFII20; TAFII-20/TAFII-15; TAFII20/TAFII15

NCBI Description

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]

Uniprot Description

TAF12: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. Belongs to the TAF12 family. 2 isoforms of the human protein are produced by alternative initiation.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: nucleoplasm; transcription factor TFIID complex

Molecular Function: DNA binding; protein binding; TATA-binding protein binding; transcription factor activity; transcription factor binding

Biological Process: positive regulation of transcription factor activity; RNA elongation from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter; transcriptional preinitiation complex assembly