Mouse anti-Human ST2/IL-1 RL1 Monoclonal Antibody | anti-IL1RL1 antibody
Anti-ST2/IL-1 RL1 Antibody, Mouse Monoclonal
Gene Names
IL1RL1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
Reactivity
Human
Applications
ELISA
Purity
Protein A
Synonyms
ST2/IL-1 RL1; Monoclonal Antibody; Anti-ST2/IL-1 RL1 Antibody; Mouse Monoclonal; IL1RL1/IL?1 R4 Antibody; Mouse MAb; interleukin 1 receptor-like 1; Anti-DER4 Antibody; Anti-FIT-1 Antibody; Anti-IL1RL1 Antibody; Anti-IL33R Antibody; Anti-IL-1 R4 Antibody; Anti-ST2 Antibody; Anti-ST2L Antibody; Anti-ST2V Antibody; Anti-T1 Antibody; anti-IL1RL1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
12
Specificity
Human IL1RL1/IL?1 R4
Purity/Purification
Protein A
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-IL1RL1 antibody
ELISA (EIA) (Det)
Application Notes
ELISA (Det): This antibody will detect Human IL1RL1/IL-1 R4 in ELISA pair set.
In a sandwich ELISA, it can be used as detection antibody when paired with.
In a sandwich ELISA, it can be used as detection antibody when paired with.
Immunogen
Recombinant Human IL1RL1/IL-1 R4 Protein
Conjugation
Unconjugated
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1/IL?1 R4 (rh IL1RL1/IL?1 R4). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-IL1RL1 antibody
IL-1 receptor-like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to identifies cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
Product Categories/Family for anti-IL1RL1 antibody
References
Savenije OE, et al. (2011) Interleukin-1 receptor-like 1 polymorphisms are associated with serum IL1RL1-a, eosinophils, and asthma in childhood. J Allergy Clin Immunol. 127(3): 750-6.Li H, et al. (2000) The cloning and nucleotide sequence of human ST2L cDNA. Genomics. 67(3): 284-90.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,358 Da
NCBI Official Full Name
interleukin-1 receptor-like 1 isoform 2
NCBI Official Synonym Full Names
interleukin 1 receptor-like 1
NCBI Official Symbol
IL1RL1
NCBI Official Synonym Symbols
T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R
NCBI Protein Information
interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed
UniProt Protein Name
Interleukin-1 receptor-like 1
Protein Family
UniProt Gene Name
IL1RL1
UniProt Synonym Gene Names
DER4; ST2; T1
UniProt Entry Name
ILRL1_HUMAN
NCBI Description
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Research Articles on IL1RL1
Similar Products
Product Notes
The IL1RL1 il1rl1 (Catalog #AAA8100936) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-ST2/IL-1 RL1 Antibody, Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ST2/IL-1 RL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA) (Det). ELISA (Det): This antibody will detect Human IL1RL1/IL-1 R4 in ELISA pair set. In a sandwich ELISA, it can be used as detection antibody when paired with. Researchers should empirically determine the suitability of the IL1RL1 il1rl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST2/IL-1 RL1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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