Mouse anti-Human, Mouse SMARCA1 Monoclonal Antibody | anti-SMARCA1 antibody
SMARCA1
NCBI and Uniprot Product Information
Uniprot Description
SMARCA1: Energy-transducing component of NURF (nucleosome- remodeling factor) and CERF (CECR2-containing-remodeling factor) complexes. Both complexes facilitate the perturbation of chromatin structure in an ATP-dependent manner. Potentiates neurite outgrowth. May be involved in brain development by regulating En-1 and En-2 expression. May be involved in the development of luteal cells. Part of the nucleosome-remodeling factor (NURF) complex which consists of SMARCA1; BPTF; RBBP4 and RBBP7. Part of the CECR2-containing-remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts with PRLR. Belongs to the SNF2/RAD54 helicase family. ISWI subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; EC 3.6.1.-; EC 3.6.4.-; Helicase; Transcription regulation
Chromosomal Location of Human Ortholog: Xq25-q26.1
Cellular Component: intracellular membrane-bound organelle; nucleoplasm; nucleus
Molecular Function: ATP binding; DNA binding; DNA-dependent ATPase activity; helicase activity; nucleosome binding; protein binding; transcription factor binding
Biological Process: ATP-dependent chromatin remodeling; brain development; chromatin remodeling; covalent chromatin modification; DNA strand renaturation; neuron differentiation; positive regulation of transcription, DNA-templated; transcription, DNA-dependent
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Product Notes
The SMARCA1 smarca1 (Catalog #AAA8564956) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SMARCA1 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "SMARCA1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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