Western Blot (WB)
(Western Blot detection against Immunogen (52.84kD).)
Mouse anti-Human SLC45A2 Monoclonal Antibody | anti-SLC45A2 antibody
SLC45A2 (Solute Carrier Family 45 Member 2, 1A1, AIM1, Membrane-associated Transporter Protein, MATP, Melanoma Antigen AIM1, Protein AIM-1, SHEP5)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot detection against Immunogen (52.84kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (52.84kD).)
Western Blot (WB)
(MATP monoclonal antibody, Western Blot analysis of MATP expression in HL-60.)
Western Blot (WB)
(MATP monoclonal antibody, Western Blot analysis of MATP expression in HL-60.)
Testing Data
(Detection limit for recombinant GST tagged SLC45A2 is ~0.1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged SLC45A2 is ~0.1ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Uniprot Description
SLC45A2: Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis. Defects in SLC45A2 are the cause of albinism oculocutaneous type 4 (OCA4). A disorder of pigmentation characterized by reduced biosynthesis of melanin in the skin, hair and eyes. Patients show reduced or lacking pigmentation associated with classic albinism ocular abnormalities, including decreased visual acuity, macular hypoplasia, optic dysplasia, atypical choroidal vessels, and nystagmus. Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5p13.2
Cellular Component: melanosome membrane; integral to membrane
Biological Process: melanin biosynthetic process; visual perception; response to stimulus
Disease: Skin/hair/eye Pigmentation, Variation In, 5; Albinism, Oculocutaneous, Type Iv
Research Articles on SLC45A2
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Product Notes
The SLC45A2 slc45a2 (Catalog #AAA6000145) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SLC45A2 (Solute Carrier Family 45 Member 2, 1A1, AIM1, Membrane-associated Transporter Protein, MATP, Melanoma Antigen AIM1, Protein AIM-1, SHEP5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC45A2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the SLC45A2 slc45a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSNSGQAGR HIYKSLADDG PFDSVEPPKR PTSRLIMHSM AMFGREFCYA VEAAYVTPVL LSVGLPSSLY SIVWFLSPIL GFLLQPVVGS ASDHCRSRWG RRRPYILTLG VMMLVGMALY LNGATVVAAL IANPRRKLVW AISVTMIGVV LFDFAADFID GPIKAYLFDV CSHQDKEKGL HYHALFTDSQ GNDIKVTAES TGEHASSLPL PLHQPPHWMD GLPVQHAVLH RFHGPDCVPR GSL. It is sometimes possible for the material contained within the vial of "SLC45A2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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