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Testing Data (L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS608115 (1:500 dilution). |Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein SG2NA (~93kD).)

Mouse SG2NA Monoclonal Antibody | anti-STRN3 antibody

SG2NA (Striatin-3, calmodulin binding protein 3, Cell-cycle autoantigen SG2NA, GS2NA, S/G2 Antigen)

Gene Names
STRN3; SG2NA
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunocytochemistry
Purity
Ascites
Ascites
Synonyms
SG2NA; Monoclonal Antibody; SG2NA (Striatin-3; calmodulin binding protein 3; Cell-cycle autoantigen SG2NA; GS2NA; S/G2 Antigen); Anti -SG2NA (Striatin-3; anti-STRN3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9H272
Specificity
Recognizes SG2NA at 93kD. Does not crossreact with striatin. Species Crossreactivity: human, rat, mouse.
Purity/Purification
Ascites
Ascites
Form/Format
Supplied as a liquid in 0.02% sodium azide, 40% glycerol.
Applicable Applications for anti-STRN3 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry.
Dilution: Western Blot: 1:1000 detected SG2NA on 10ug of L6 lysates. Recgonizes SG2NA at ~93kD in Jurkat cell lysate. In some cell types, a band of ~70kD is also recognized, which may be an alternatively splliced form of SG2NA or another unknown protein.
Immunoprecipitation: 3ul
Immunocytochemistry: 1:500
Immunogen
Synthetic peptide from SG2NA. Cellular Localization: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity).
Positive Control
L6 cell lysate
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 

Testing Data

(L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS608115 (1:500 dilution). |Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein SG2NA (~93kD).)

Testing Data (L6 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with MBS608115 (1:500 dilution). |Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates protein SG2NA (~93kD).)

Testing Data

(RAW 264 lysate (Lane1), NIH/3T3 lysate (Lane 2), C2C12 lysate (Lane 3), PC12 lysate (Lane 4), L6 lysate (Lane 5) and HepG2 lysate (Lane 6) were resolved by electrophoresis, transferred to PVDF membrane and probed with MBS608115 (1:500). Proteins were visualized using a Gt xMo IgG (HRP) and a chemiluminescence detection system. Arrow indicates protein SG2NA (~93kD).)

Testing Data (RAW 264 lysate (Lane1), NIH/3T3 lysate (Lane 2), C2C12 lysate (Lane 3), PC12 lysate (Lane 4), L6 lysate (Lane 5) and HepG2 lysate (Lane 6) were resolved by electrophoresis, transferred to PVDF membrane and probed with MBS608115 (1:500). Proteins were visualized using a Gt xMo IgG (HRP) and a chemiluminescence detection system. Arrow indicates protein SG2NA (~93kD).)
Related Product Information for anti-STRN3 antibody
SG2NA, also known as Striatin 3, was identified as a human cancer auto-antigen and has not been implicated in vesicular trafficking and signal tranduction. It is highly related to striatin and zinedin (striatin 4). It is a cytoplasmic scaffolding protein that binds to Calmodulin and PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which appears to modulate PP2A activity.
Product Categories/Family for anti-STRN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
87,209 Da
NCBI Official Full Name
striatin-3 isoform 1
NCBI Official Synonym Full Names
striatin, calmodulin binding protein 3
NCBI Official Symbol
STRN3
NCBI Official Synonym Symbols
SG2NA
NCBI Protein Information
striatin-3; s/G2 antigen; nuclear autoantigen; cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen
UniProt Protein Name
Striatin-3
Protein Family
UniProt Gene Name
STRN3
UniProt Synonym Gene Names
GS2NA; SG2NA
UniProt Entry Name
STRN3_HUMAN

Uniprot Description

SG2NA: a protein of the WD-repeat striatin family. Mainly expressed within neurons and thought to act both as scaffolds and as Ca(2+)-dependent signalling proteins. May interact with protein phosphatase 2A. Two alternatively spliced isoforms have been described.

Protein type: Transcription factor; Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q13-q21

Cellular Component: nucleoplasm; Golgi apparatus; protein phosphatase type 2A complex; protein complex; cell soma; dendrite; cytoplasm; plasma membrane; nucleus

Molecular Function: calmodulin binding; protein binding; protein phosphatase 2A binding; protein complex binding; transcription factor activity

Biological Process: positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to estradiol stimulus; negative regulation of estrogen receptor signaling pathway

Similar Products

Product Notes

The STRN3 strn3 (Catalog #AAA608115) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SG2NA (Striatin-3, calmodulin binding protein 3, Cell-cycle autoantigen SG2NA, GS2NA, S/G2 Antigen) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SG2NA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC). Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Dilution: Western Blot: 1:1000 detected SG2NA on 10ug of L6 lysates. Recgonizes SG2NA at ~93kD in Jurkat cell lysate. In some cell types, a band of ~70kD is also recognized, which may be an alternatively splliced form of SG2NA or another unknown protein. Immunoprecipitation: 3ul Immunocytochemistry: 1:500. Researchers should empirically determine the suitability of the STRN3 strn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SG2NA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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