Mouse anti-Human SERPINH1 Monoclonal Antibody | anti-SERPINH1 antibody

SERPINH1 (Serpin H1, Collagen-binding Protein, Colligin, 47kD Heat Shock Protein, Rheumatoid Arthritis-related Antigen RA-A47, Arsenic-transactivated Protein 3, AsTP3, Cell Proliferation-inducing Gene 14 Protein, PIG14, SERPINH2, HSP47, CBP2, CBP1) APC

Cat. Num. AAA6135066

• Gene Names: SERPINH1; CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2
• Reactivity: Human
• Applications: ELISA, Immunohistochemistry, Western Blot
• Purity: Purified
• Synonyms: SERPINH1; Monoclonal Antibody; SERPINH1 (Serpin H1; Collagen-binding Protein; Colligin; 47kD Heat Shock Protein; Rheumatoid Arthritis-related Antigen RA-A47; Arsenic-transactivated Protein 3; AsTP3; Cell Proliferation-inducing Gene 14 Protein; PIG14; SERPINH2; HSP47; CBP2; CBP1) APC; anti-SERPINH1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 1D2-1A6
• Specificity: Recognizes human SERPINH1.
• Purity/Purification: Purified
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 418

• Applicable Applications for anti-SERPINH1 antibody: ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: SERPINH1 (AAH14623, 1-419aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26kD.
• Conjugate: APC
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Related Product Information for anti-SERPINH1 antibody

SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis.

Product Categories/Family for anti-SERPINH1 antibody

Antibodies; Heat Shock Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 15779117
• NCBI GeneID: 871
• NCBI Official Full Name: Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
• NCBI Official Synonym Full Names: serpin family H member 1
• NCBI Official Symbol: SERPINH1
• NCBI Official Synonym Symbols: CBP1; CBP2; OI10; gp46; AsTP3; HSP47; PIG14; PPROM; RA-A47; SERPINH2
• NCBI Protein Information: serpin H1
• Protein Family: Serpin

NCBI Description

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]