Mouse anti-Human SERPINB9 Monoclonal Antibody | anti-SERPINB9 antibody
SERPINB9 (Serine/Cysteine Proteinase Inhibitor Clade B Member 9, Serpin Peptidase Inhibitor Clade B (Ovalbumin) Member 9, Serpin B9, Cytoplasmic Antiproteinase 3, CAP3, CAP-3, Peptidase Inhibitor 9, Proteinase Inhibitor 9, PI9, PI-9)
Gene Names
SERPINB9; PI9; CAP3; CAP-3
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Functional Assay
Purity
SupernatantSupernatant
Synonyms
SERPINB9; Monoclonal Antibody; SERPINB9 (Serine/Cysteine Proteinase Inhibitor Clade B Member 9; Serpin Peptidase Inhibitor Clade B (Ovalbumin) Member 9; Serpin B9; Cytoplasmic Antiproteinase 3; CAP3; CAP-3; Peptidase Inhibitor 9; Proteinase Inhibitor 9; PI9; PI-9); Anti -SERPINB9 (Serine/Cysteine Proteinase Inhibitor Clade B Member 9; anti-SERPINB9 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
Pi9-17
Specificity
Recognizes human SERPINB9.
Purity/Purification
Supernatant
Supernatant
Supernatant
Form/Format
Supplied as a liquid in 0.7% BSA, 0.1% sodium azide.
Applicable Applications for anti-SERPINB9 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Not suitable for use in Flow Cytometry.
Dilution: Western Blot: Detects native SERPINB9 at 4~2kD as well as SERPINB9 complexed to granzyme B at ~67kD. As a positive control for SERPINB9, YT-Indy cells (a natural killer leukemia cell line) can be used. In other cell lines a non-specific protein band of ~63kD can be detected.
Immunohistochemistry: 1:100 Can be used on formaldehyde-fixed paraffin-embedded human tissues after pretreatment with 10mM citric acid pH 6.0 for 20 min.
Immunocytochemistry: Fix cells for 10 min in 10% formalin and then treat them as paraffin sections.
Dilution: Western Blot: Detects native SERPINB9 at 4~2kD as well as SERPINB9 complexed to granzyme B at ~67kD. As a positive control for SERPINB9, YT-Indy cells (a natural killer leukemia cell line) can be used. In other cell lines a non-specific protein band of ~63kD can be detected.
Immunohistochemistry: 1:100 Can be used on formaldehyde-fixed paraffin-embedded human tissues after pretreatment with 10mM citric acid pH 6.0 for 20 min.
Immunocytochemistry: Fix cells for 10 min in 10% formalin and then treat them as paraffin sections.
Immunogen
Full length recombinant SERPINB9 produced in E. coli.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Product Categories/Family for anti-SERPINB9 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,404 Da
NCBI Official Full Name
serpin B9
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 9
NCBI Official Symbol
SERPINB9
NCBI Official Synonym Symbols
PI9; CAP3; CAP-3
NCBI Protein Information
serpin B9; PI-9; OTTHUMP00000015954; peptidase inhibitor 9; cytoplasmic antiproteinase 3; protease inhibitor 9 (ovalbumin type); serpin peptidase inhibitor, clade B, member 9; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9
UniProt Protein Name
Serpin B9
Protein Family
UniProt Gene Name
SERPINB9
UniProt Synonym Gene Names
PI9
UniProt Entry Name
SPB9_HUMAN
NCBI Description
PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis (Sprecher et al., 1995 [PubMed 8530382]).[supplied by OMIM]
Uniprot Description
SERPINB9: Granzyme B inhibitor. Belongs to the serpin family. Ov-serpin subfamily.
Chromosomal Location of Human Ortholog: 6p25
Cellular Component: extracellular space; membrane; cytoplasm; intracellular; cytosol; nucleus
Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protease binding; caspase inhibitor activity
Biological Process: mast cell mediated immunity; response to bacterium; immune response; negative regulation of caspase activity; negative regulation by symbiont of host apoptosis; protection from natural killer cell mediated cytotoxicity; negative regulation of apoptosis
Research Articles on SERPINB9
Similar Products
Product Notes
The SERPINB9 serpinb9 (Catalog #AAA609428) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SERPINB9 (Serine/Cysteine Proteinase Inhibitor Clade B Member 9, Serpin Peptidase Inhibitor Clade B (Ovalbumin) Member 9, Serpin B9, Cytoplasmic Antiproteinase 3, CAP3, CAP-3, Peptidase Inhibitor 9, Proteinase Inhibitor 9, PI9, PI-9) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINB9 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS). Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Not suitable for use in Flow Cytometry. Dilution: Western Blot: Detects native SERPINB9 at 4~2kD as well as SERPINB9 complexed to granzyme B at ~67kD. As a positive control for SERPINB9, YT-Indy cells (a natural killer leukemia cell line) can be used. In other cell lines a non-specific protein band of ~63kD can be detected. Immunohistochemistry: 1:100 Can be used on formaldehyde-fixed paraffin-embedded human tissues after pretreatment with 10mM citric acid pH 6.0 for 20 min. Immunocytochemistry: Fix cells for 10 min in 10% formalin and then treat them as paraffin sections. Researchers should empirically determine the suitability of the SERPINB9 serpinb9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINB9, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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