Mouse anti-Human RNASEH2A Monoclonal Antibody | anti-RNASEH2A antibody

RNASEH2A (Ribonuclease H2 Subunit A, RNase H2 Subunit A, Ribonuclease HI Subunit A, Ribonuclease HI Large Subunit, RNase HI Large Subunit, RNase H(35), Aicardi-Goutieres Syndrome 4 Protein, AGS4, RNASEHI, RNHIA) APC

Cat. Num. AAA6138748

• Gene Names: RNASEH2A; AGS4; JUNB; RNHL; RNHIA; RNASEHI
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: RNASEH2A; Monoclonal Antibody; RNASEH2A (Ribonuclease H2 Subunit A; RNase H2 Subunit A; Ribonuclease HI Subunit A; Ribonuclease HI Large Subunit; RNase HI Large Subunit; RNase H(35); Aicardi-Goutieres Syndrome 4 Protein; AGS4; RNASEHI; RNHIA) APC; anti-RNASEH2A antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 3G5-F5
• Specificity: Recognizes human RNASEH2A.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-RNASEH2A antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-299 from RNASEH2A (AAH11748) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MDLSELERDNTGRCRLSSPVPAVCRKEPCVLGVDEAGRGPVLGPMVYAICYCPLPRLADLEALKVADSKTLLESERERLFAKMEDTDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTATGLIQYALDQGVNVTQVFVDTVGMPETYQARLQQSFPGIEVTVKAKADALYPVVSAASICAKVARDQAVKKWQFVEKLQDLDTDYGSGYPNDPKTKAWLKEHVEPVFGFPQFVRFSWRTAQTILEKEAEDVIWEDSASENQEGLRKITSYFLNEGSQARPRSSHRYFLERGLESATSL
• Conjugate: APC
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (59kD).)

Western Blot (WB)

(RNASEH2A monoclonal antibody Western Blot analysis of RNASEH2A expression in Jurkat.)

Product Categories/Family for anti-RNASEH2A antibody

Antibodies; Disease Markers

NCBI and Uniprot Product Information

• NCBI GI #: 33873385
• NCBI GeneID: 10535
• Molecular Weight: 33,395 Da
• NCBI Official Full Name: Homo sapiens ribonuclease H2, subunit A, mRNA
• NCBI Official Synonym Full Names: ribonuclease H2 subunit A
• NCBI Official Symbol: RNASEH2A
• NCBI Official Synonym Symbols: AGS4; JUNB; RNHL; RNHIA; RNASEHI
• NCBI Protein Information: ribonuclease H2 subunit A
• Protein Family: Ribonuclease

NCBI Description

The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009]