Western Blot (WB)
(Western Blot detection against Immunogen (33.15kD).)
Mouse anti-Human RING Finger Protein 181 Monoclonal Antibody | anti-RNF181 antibody
RING Finger Protein 181 (RNF181, E3 Ubiquitin-protein Ligase RNF181, HSPC238) (AP)
Western Blot (WB)
(Western Blot detection against Immunogen (33.15kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (33.15kD).)
Western Blot (WB)
(RNF181 monoclonal antibody, Western Blot analysis of RNF181 expression in Jurkat.)
Western Blot (WB)
(RNF181 monoclonal antibody, Western Blot analysis of RNF181 expression in Jurkat.)
Western Blot (WB)
(Western Blot analysis of RNF181 expression in transfected 293T cell line by RNF181 monoclonal antibody. Lane 1: RNF181 transfected lysate (17.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of RNF181 expression in transfected 293T cell line by RNF181 monoclonal antibody. Lane 1: RNF181 transfected lysate (17.9kD). Lane 2: Non-transfected lysate.)
Immunoprecipitation (IP)
(Immunoprecipitation of RNF181 transfected lysate using RNF181 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with RNF181 monoclonal antibody.)
Immunoprecipitation (IP)
(Immunoprecipitation of RNF181 transfected lysate using RNF181 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with RNF181 monoclonal antibody.)
Testing Data
(Detection limit for recombinant GST tagged RNF181 is ~0.1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged RNF181 is ~0.1ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008]
Uniprot Description
RNF181: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Belongs to the RNF181 family.
Protein type: Ligase; Ubiquitin ligase; EC 6.3.2.-; Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 2p11.2
Molecular Function: zinc ion binding; ubiquitin-protein ligase activity; ligase activity
Biological Process: protein autoubiquitination
Research Articles on RNF181
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Product Notes
The RNF181 rnf181 (Catalog #AAA6133473) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RING Finger Protein 181 (RNF181, E3 Ubiquitin-protein Ligase RNF181, HSPC238) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RING Finger Protein 181 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the RNF181 rnf181 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RING Finger Protein 181, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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