Immunohistochemistry (IHC)
(Anti-PTGES3 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Mouse PTGES3 Monoclonal Antibody | anti-PTGES3 antibody
Mouse Monoclonal [clone JJ6] (IgG1) to Human PTGES3
Gene Names
PTGES3; P23; TEBP; cPGES
Reactivity
Chicken, Guinea pig, Human, Mouse, Pig, Rabbit, Yeast
Applications
Immunohistochemistry, Western Blot, Immunoprecipitation, ELISA
Purity
Protein G Purified
Synonyms
PTGES3; Monoclonal Antibody; Mouse Monoclonal [clone JJ6] (IgG1) to Human PTGES3; Anti-PTGES3 Antibody (clone JJ6) IHC-plus; CPGES; p23; Prostaglandin E synthase 3; Telomerase-binding protein p23; Hsp90 co-chaperone; TEBP; Human PTGES3; anti-PTGES3 antibody
Host
Mouse
Reactivity
Chicken, Guinea pig, Human, Mouse, Pig, Rabbit, Yeast
Clonality
Monoclonal
Isotype
IgG1
Clone Number
JJ6
Specificity
Detects ~23 kD protein.
Purity/Purification
Protein G Purified
Form/Format
PBS, 0.09% sodium azide in 50% glycerol. Sourced in Ascites.
Concentration
1 mg/ml (varies by lot)
Sequence Length
160
Applicable Applications for anti-PTGES3 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
Application Notes
ELISA, IHC-P (10 ug/ml), IP, WB (1:2000)
Target Species
Human
Immunogen Description
Recombinant Human full length p23 protein.
Immunogen Type
Recombinant protein
Immunogen
PTGES3 antibody was raised against recombinant Human full length p23 protein.
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
Immunohistochemistry (IHC)
(Anti-PTGES3 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Immunohistochemistry (IHC)
(Anti-PTGES3 antibody IHC of human testis, seminiferous ducts. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Western Blot (WB)
(P23 (JJ6), Human cell line mix.)
Western Blot (WB)
(P23 (JJ6), Human cell line mix.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,476 Da
NCBI Official Full Name
prostaglandin E synthase 3 isoform a
NCBI Official Synonym Full Names
prostaglandin E synthase 3 (cytosolic)
NCBI Official Symbol
PTGES3
NCBI Official Synonym Symbols
P23; TEBP; cPGES
NCBI Protein Information
prostaglandin E synthase 3; Hsp90 co-chaperone; telomerase-binding protein p23; progesterone receptor complex p23; cytosolic prostaglandin E synthase; cytosolic prostaglandin E2 synthase; unactive progesterone receptor, 23 kD
UniProt Protein Name
Prostaglandin E synthase 3
Protein Family
UniProt Gene Name
PTGES3
UniProt Synonym Gene Names
P23; TEBP; cPGES
UniProt Entry Name
TEBP_HUMAN
Uniprot Description
TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.
Protein type: Chaperone; Isomerase; EC 5.3.99.3; Nuclear receptor co-regulator; Transferase
Chromosomal Location of Human Ortholog: 12q13.3|12
Cellular Component: nucleoplasm; chromosome, telomeric region; cytoplasm; telomerase holoenzyme complex; nucleus; cytosol
Molecular Function: telomerase activity; protein binding; unfolded protein binding; prostaglandin-E synthase activity
Biological Process: RNA-dependent DNA replication; cyclooxygenase pathway; arachidonic acid metabolic process; prostaglandin biosynthetic process; signal transduction; telomere maintenance
Research Articles on PTGES3
1. FKBP4, p23, and Aha1 cooperatively regulate the progression of hAgo2 through the chaperone cycle.
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Product Notes
The PTGES3 ptges3 (Catalog #AAA246542) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone JJ6] (IgG1) to Human PTGES3 reacts with Chicken, Guinea pig, Human, Mouse, Pig, Rabbit, Yeast and may cross-react with other species as described in the data sheet. AAA Biotech's PTGES3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA). ELISA, IHC-P (10 ug/ml), IP, WB (1:2000). Researchers should empirically determine the suitability of the PTGES3 ptges3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTGES3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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