Western Blot (WB)
(Western Blot detection against Immunogen (71.87kD).)
Mouse anti-Human, Mouse PSTPIP1 Monoclonal Antibody | anti-PSTPIP1 antibody
PSTPIP1 (Proline-serine-threonine Phosphatase-interacting Protein 1, PEST Phosphatase-interacting Protein 1, PSTPIP, CD2-binding Protein 1, CD2BP1, H-PIP) (AP)
Western Blot (WB)
(Western Blot detection against Immunogen (71.87kD).)
Western Blot (WB)
(Western Blot detection against Immunogen (71.87kD).)
Western Blot (WB)
(PSTPIP1 monoclonal antibody Western Blot analysis of PSTPIP1 expression in Raw 264.7)
Western Blot (WB)
(PSTPIP1 monoclonal antibody Western Blot analysis of PSTPIP1 expression in Raw 264.7)
Testing Data
(Detection limit for recombinant GST tagged PSTPIP1 is 1ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PSTPIP1 is 1ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a cytoskeletal protein that is highly expressed in hemopoietic tissues. This protein functions via its interaction with several different proteins involved in cytoskeletal organization and inflammatory processes. It binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, downregulating CD2-triggered adhesion. It binds PEST-type protein tyrosine phosphatases (PTP) and directs them to c-Abl kinase to mediate c-Abl dephosphorylation, thereby, regulating c-Abl activity. It also interacts with pyrin, which is found in association with the cytoskeleton in myeloid/monocytic cells and modulates immunoregulatory functions. Mutations in this gene are associated with PAPA (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) syndrome. It is hypothesized that the disease-causing mutations compromise physiologic signaling necessary for the maintenance of a proper inflammatory response. [provided by RefSeq, Mar 2016]
Research Articles on PSTPIP1
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Product Notes
The PSTPIP1 (Catalog #AAA6133198) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PSTPIP1 (Proline-serine-threonine Phosphatase-interacting Protein 1, PEST Phosphatase-interacting Protein 1, PSTPIP, CD2-binding Protein 1, CD2BP1, H-PIP) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PSTPIP1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PSTPIP1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSTPIP1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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