Western Blot (WB)
(PSMC2 monoclonal antibody Western Blot analysis of PSMC2 expression in SW-13.)
Mouse anti-Human PSMC2 Monoclonal Antibody | anti-PSMC2 antibody
PSMC2 (26S Protease Regulatory Subunit 7, Proteasome 26S Subunit ATPase 2, 26S Proteasome AAA-ATPase Subunit RPT1, Protein MSS1, MSS1) (AP)
Western Blot (WB)
(PSMC2 monoclonal antibody Western Blot analysis of PSMC2 expression in SW-13.)
Western Blot (WB)
(PSMC2 monoclonal antibody Western Blot analysis of PSMC2 expression in SW-13.)
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to PSMC2 on HeLa cell. [antibody concentration 10ug/ml])
Immunofluorescence (IF)
(Immunofluorescence of monoclonal antibody to PSMC2 on HeLa cell. [antibody concentration 10ug/ml])
Testing Data
(Detection limit for recombinant GST tagged PSMC2 is 0.3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PSMC2 is 0.3ng/ml as a capture antibody.)
NCBI and Uniprot Product Information
NCBI Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011]
Research Articles on PSMC2
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Product Notes
The PSMC2 (Catalog #AAA6133187) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PSMC2 (26S Protease Regulatory Subunit 7, Proteasome 26S Subunit ATPase 2, 26S Proteasome AAA-ATPase Subunit RPT1, Protein MSS1, MSS1) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSMC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PSMC2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMC2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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