Western Blot (WB)
(Western blot detection of Protein CASP in Hela,A549,HL-60,U2OS,C6 cell lysates using Protein CASP Rabbit mAb(1:1000 diluted). Predicted band size:78kDa. Observed band size:78kDa.)
Rabbit Protein CASP Monoclonal Antibody | anti-CASP antibody
Protein CASP Rabbit mAb
ICC/IF: 1:20
FC: 1:20
IP: 1:20
Western Blot (WB)
(Western blot detection of Protein CASP in Hela,A549,HL-60,U2OS,C6 cell lysates using Protein CASP Rabbit mAb(1:1000 diluted). Predicted band size:78kDa. Observed band size:78kDa.)
Western Blot (WB)
(Western blot detection of Protein CASP in Hela,A549,HL-60,U2OS,C6 cell lysates using Protein CASP Rabbit mAb(1:1000 diluted). Predicted band size:78kDa. Observed band size:78kDa.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
Uniprot Description
CUTL1 iso1: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Belongs to the CUT homeobox family. 8 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 7q22.1
Cellular Component: integral to Golgi membrane; cytosol; nucleus
Molecular Function: sequence-specific DNA binding; chromatin binding
Biological Process: regulation of transcription from RNA polymerase II promoter; intra-Golgi vesicle-mediated transport; transcription, DNA-dependent; multicellular organismal development; positive regulation of transcription from RNA polymerase II promoter; auditory receptor cell differentiation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite morphogenesis; kidney development; lung development
Research Articles on CASP
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Product Notes
The CASP cux1 (Catalog #AAA4753409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Protein CASP Rabbit mAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Protein CASP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP). WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20. Researchers should empirically determine the suitability of the CASP cux1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein CASP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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