Mouse anti-Human Protein C/APC (Calcium Dependent) Monoclonal Antibody
Anti-Human Protein C/APC (Calcium Dependent), Purified (Clone: CaC-11) (Mouse IgG1)
Reactivity
Human
Applications
ELISA, Western Blot
Synonyms
Protein C/APC (Calcium Dependent); Monoclonal Antibody; Anti-Human Protein C/APC (Calcium Dependent); Purified (Clone: CaC-11) (Mouse IgG1); Anti-Human Protein C/APC; anti-Protein C/APC (Calcium Dependent) antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
CaC-11
Specificity
Protein C/APC (Calcium Dependent) (This antibody is specific for Human Protein C/APC in the presence of 5-10 mM CaCl2.)
Form/Format
Purified
Concentration
1.0 mg/ml (varies by lot)
Applicable Applications for anti-Protein C/APC (Calcium Dependent) antibody
ELISA (EIA), Western Blot (WB)
Application Notes
This antibody is suitable for use in ELISA and Western Blot.
Immunogen
Human Protein C purified from the supernatant of thrombin activated platelets.
Presentation
Purified IgG buffered in PBS and 0.02% NaN3. (Purified from ascitic fluid via Protein G Chromatography).
Preparation and Storage
Store at +4 degree C. For long term storage, aliquot and freeze unused portion at -20 degree C in volumes appropriate for single use. Avoid freeze thaw cycles.
Related Product Information for anti-Protein C/APC (Calcium Dependent) antibody
Protein C (PC) is a major physiological anticoagulant, and an important regulator of the blood coagulation system. PC is a vitamin K dependent serine protease enzyme that is activated by thrombin. The anticoagulant PC is converted to activated protein C (APC) by the thrombomodulin (TM) - thrombin complex on the phospholipid surface of endothelial cells, monocytes and platelets. APC degrades coagulation Factors Va and VIIIa rendering these factors inactive. APC provides physiologic antithrombotic activity and exhibits both anti-inflammatory and anti-apoptotic activity. Treatment with APC has been shown to improve the clinical outcome of patients with sepsis.
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Product Notes
The Protein C/APC (Calcium Dependent) (Catalog #AAA520502) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-Human Protein C/APC (Calcium Dependent), Purified (Clone: CaC-11) (Mouse IgG1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Protein C/APC (Calcium Dependent) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). This antibody is suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the Protein C/APC (Calcium Dependent) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein C/APC (Calcium Dependent), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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