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Mouse anti-Human ProCollagen Type I Propeptide Monoclonal Antibody | anti-Pcolce antibody

ProCollagen Type I Propeptide, CT (PICP)

Gene Names
Pcolce; P14; Astt2; Astt-2; PCPE-1
Reactivity
Human
Applications
ELISA
Purity
Affinity Purified
Purified by Protein A/G affinity chromatography.
Synonyms
ProCollagen Type I Propeptide; Monoclonal Antibody; CT (PICP); Anti -ProCollagen Type I Propeptide; anti-Pcolce antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
6F175
Specificity
Recognizes native human Procollagen type I C-terminal propeptide (PICP) from amniotic fluid.
Purity/Purification
Affinity Purified
Purified by Protein A/G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
Concentration
0.97 mg/ml (varies by lot)
Applicable Applications for anti-Pcolce antibody
Suitable for use in ELISA. Other applications not tested.
Application Notes
Optimal dilutions to be determined by the researcher.
Immunogen
PICP purified from second trimester amniotic fluid.
Culture Medium
RPMI 1640 with 10% fetal calf serum
Hybridoma
X63-Ag8.653 myeloma cells with spleen cells from Balb/c mice.
Preparation and Storage
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Related Product Information for anti-Pcolce antibody
Collagen type I is present in soft connective tissue and bone where it represents approximately 90% of the organic matrix. Collagen type I is produced from procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. The propeptide levels can be measured in serum as indicators of collagen production. Elevated values of these propeptides in serum are found in patients with various bone metabolism defects. Procollagen type I C-terminal propeptide (PICP) has a molecular weight of ~100kD and the normal range in serum is 100-300ug/ml.
Product Categories/Family for anti-Pcolce antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Procollagen C-endopeptidase enhancer 1
NCBI Official Synonym Full Names
procollagen C-endopeptidase enhancer protein
NCBI Official Symbol
Pcolce
NCBI Official Synonym Symbols
P14; Astt2; Astt-2; PCPE-1
NCBI Protein Information
procollagen C-endopeptidase enhancer 1; astroglial cell transcript 2; procollagen C-proteinase enhancer 1; procollagen C-proteinase enhancer protein; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer
UniProt Protein Name
Procollagen C-endopeptidase enhancer 1
UniProt Gene Name
Pcolce
UniProt Synonym Gene Names
Pcpe1; PCPE-1
UniProt Entry Name
PCOC1_MOUSE

Uniprot Description

PCOLCE: Binds to the C-terminal propeptide of type I procollagen and enhances procollagen C-proteinase activity.

Protein type: Secreted; Extracellular matrix; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; extracellular region

Molecular Function: collagen binding; heparin binding; protease activator activity

Biological Process: proteolysis

Research Articles on Pcolce

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Product Notes

The Pcolce pcolce (Catalog #AAA6009023) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ProCollagen Type I Propeptide, CT (PICP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ProCollagen Type I Propeptide can be used in a range of immunoassay formats including, but not limited to, Suitable for use in ELISA. Other applications not tested. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Pcolce pcolce for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ProCollagen Type I Propeptide, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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