Mouse anti-Human Pregnancy Associated Plasma Protein A Monoclonal Antibody | anti-PAPP-A antibody
Pregnancy Associated Plasma Protein A (PAPP-A, Pappalysin 1, PAPA, PAPPA, PAPP-A, PAPPA1, Aspecific BCL2 ARE-binding Protein 2, ASBABP2, Differentially Placenta 1 Expressed Protein, DIPLA1, EC 3.4.24.79, IGF-dependent IGFBP-4 Protease, IGFBP-4ase, Insulin
Reactivity
Human
Applications
ELISA
Purity
Purified by protein A affintiy Chromatography. Purity is tested by SDS-PAGE, ~90%.
Synonyms
Pregnancy Associated Plasma Protein A; Monoclonal Antibody; Pregnancy Associated Plasma Protein A (PAPP-A; Pappalysin 1; PAPA; PAPPA; PAPP-A; PAPPA1; Aspecific BCL2 ARE-binding Protein 2; ASBABP2; Differentially Placenta 1 Expressed Protein; DIPLA1; EC 3.4.24.79; IGF-dependent IGFBP-4 Protease; IGFBP-4ase; Insulin; anti-PAPP-A antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
1.B.130
Specificity
Recognizes human PAPP-A antigen.
Purity/Purification
Purified by protein A affintiy Chromatography. Purity is tested by SDS-PAGE, ~90%.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. No stabilizing proteins added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PAPP-A antibody
ELISA (EIA)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Purified human PAPP-A /pro MBP heterotetrameric complex (htPAPP-A)
Conjugate
AP
Hybridoma
Hybridization of Sp 2/0 myeloma cells with spleen cells from Balb/c mice.
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing alkaline phosphatase conjugates will result in a substantial loss of activity.
Related Product Information for anti-PAPP-A antibody
PAPP A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) was originally isolated from pregnancy serum as heterotetrameric protein complex with molecular weight approximately 500kD, consisting of two PAPP A subunits disulfide-linked with two subunits of the proform of eosinophil major basic protein (proMBP). In such a complex proMBP functions as an inhibitor of PAPP A proteinase activity. PAPP A is widely used as a marker of some pathologies during pregnancy. Low maternal serum levels of PAPP-A in first trimester biochemical screening is used as a marker of Down's syndrome (Trisomy 21).
Product Categories/Family for anti-PAPP-A antibody
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Product Notes
The PAPP-A (Catalog #AAA6126434) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Pregnancy Associated Plasma Protein A (PAPP-A, Pappalysin 1, PAPA, PAPPA, PAPP-A, PAPPA1, Aspecific BCL2 ARE-binding Protein 2, ASBABP2, Differentially Placenta 1 Expressed Protein, DIPLA1, EC 3.4.24.79, IGF-dependent IGFBP-4 Protease, IGFBP-4ase, Insulin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Pregnancy Associated Plasma Protein A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PAPP-A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pregnancy Associated Plasma Protein A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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