Mouse anti-Human, Mouse PRDM10 Monoclonal Antibody | anti-PRDM10 antibody

PRDM10 (PR Domain Zinc Finger Protein 10, PR Domain-containing Protein 10, Tristanin, KIAA1231, PFM7, TRIS) (FITC)

Cat. Num. AAA6121281

• Gene Names: PRDM10; PFM7
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein G Affinity Chromatography
• Synonyms: PRDM10; Monoclonal Antibody; PRDM10 (PR Domain Zinc Finger Protein 10; PR Domain-containing Protein 10; Tristanin; KIAA1231; PFM7; TRIS) (FITC); anti-PRDM10 antibody

• Host: Mouse
• Reactivity: Human, Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: 10i62
• Specificity: Recognizes human PRDM10. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein G Affinity Chromatography
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).

• Applicable Applications for anti-PRDM10 antibody: FLISA, Western Blot (WB)
• Application Notes: FLISA: 1:1,000; WB: 1:100-1:500; Applications are based on unconjugated antibody.
• Immunogen: Purified recombinant GST fusion protein encoding the N-terminal part of human PRDM10.
• Conjugate: FITC
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western analysis of extracts from 293 cells using PRDM10 antibody.)

Product Categories/Family for anti-PRDM10 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

References

1. Siegel, D.A., et al., Int. J. Dev. Neurosci. 20(3-5), 373-389 (2002).

NCBI and Uniprot Product Information

• NCBI GI #: 41349458
• NCBI GeneID: 56980
• NCBI Accession #: NP_064613.2
• NCBI GenBank Nucleotide #: NM_020228.2
• UniProt Accession #: Q9NQV6; Q17R90; Q2KHR4; Q863Z2; Q9NXI4; Q9ULI9; B7ZL71; G3XAE5; J3KP23
• Molecular Weight: 131,349 Da
• NCBI Official Full Name: PR domain zinc finger protein 10 isoform 1
• NCBI Official Synonym Full Names: PR/SET domain 10
• NCBI Official Symbol: PRDM10
• NCBI Official Synonym Symbols: PFM7
• NCBI Protein Information: PR domain zinc finger protein 10
• UniProt Protein Name: PR domain zinc finger protein 10
• Protein Family: PR domain zinc finger protein
• UniProt Gene Name: PRDM10
• UniProt Synonym Gene Names: KIAA1231; PFM7; TRIS

NCBI Description

The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Uniprot Description

PRDM10: May be involved in transcriptional regulation. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: C2H2-type zinc finger protein; Methyltransferase, protein lysine, predicted; Transcription regulation

Chromosomal Location of Human Ortholog: 11q24.3

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; methyltransferase activity; protein binding

Biological Process: methylation; regulation of transcription, DNA-templated; transcription, DNA-dependent