Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human uterus tissue using PPAR Delta Monoclonal Antibody at dilution of 1:200.)

Mouse PPAR Delta Monoclonal Antibody | anti-PPAR Delta antibody

PPAR Delta Monoclonal Antibody

Gene Names
PPARD; FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence
Purity
Protein A Purification
Synonyms
PPAR Delta; Monoclonal Antibody; PPAR Delta Monoclonal Antibody; Peroxisome proliferator-activated receptor delta (PPAR-delta) (NUCI) (Nuclear hormone receptor 1) (NUC1) (Nuclear receptor subfamily 1 group C member 2) (Peroxisome proliferator-activated receptor beta) (PPAR-beta); anti-PPAR Delta antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
5F4
Purity/Purification
Protein A Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
441
Applicable Applications for anti-PPAR Delta antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF)
Application Notes
IHC: 1:100-200
IF: 1:100-200
Immunogen
Recombinant Protein of PPAR Delta of PPAR Delta
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human uterus tissue using PPAR Delta Monoclonal Antibody at dilution of 1:200.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human uterus tissue using PPAR Delta Monoclonal Antibody at dilution of 1:200.)

Immunofluorescence (IF)

(Immunofluorescence analysis of Mouse spleen tissue using PPAR Delta Monoclonal Antibody at dilution of 1:200.)

Immunofluorescence (IF) (Immunofluorescence analysis of Mouse spleen tissue using PPAR Delta Monoclonal Antibody at dilution of 1:200.)
Related Product Information for anti-PPAR Delta antibody
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,855 Da
NCBI Official Full Name
peroxisome proliferator-activated receptor delta isoform 1
NCBI Official Synonym Full Names
peroxisome proliferator activated receptor delta
NCBI Official Symbol
PPARD
NCBI Official Synonym Symbols
FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB
NCBI Protein Information
peroxisome proliferator-activated receptor delta
UniProt Protein Name
Peroxisome proliferator-activated receptor delta
UniProt Gene Name
PPARD
UniProt Synonym Gene Names
NR1C2; PPARB; PPAR-delta; NUC1; PPAR-beta

NCBI Description

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017]

Uniprot Description

Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.

Research Articles on PPAR Delta

Similar Products

Product Notes

The PPAR Delta ppard (Catalog #AAA2548903) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PPAR Delta Monoclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PPAR Delta can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF). IHC: 1:100-200 IF: 1:100-200. Researchers should empirically determine the suitability of the PPAR Delta ppard for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPAR Delta, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.