Mouse anti-Human PKD1L2 Monoclonal Antibody | anti-PKD1L2 antibody
PKD1L2 (Polycystic Kidney Disease Protein 1-like 2, PC1-like 2 Protein, Polycystin-1L2, KIAA1879, PC1L2, DKFZp686J19100, FLJ45333)
Ascites
Ascites
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Uniprot Description
Function: May function as an ion-channel regulator. May function as a G-protein-coupled receptor. Ref.3
Subunit structure: May interact via its C-terminus with GNAS and GNAI1. Ref.3
Subcellular location: Membrane; Multi-pass membrane protein
Potential.
Tissue specificity: Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney. Ref.1
Developmental stage: Expressed in fetal heart.
Sequence similarities: Belongs to the polycystin family.Contains 1 C-type lectin domain.Contains 1 GPS domain.Contains 1 PLAT domain.Contains 1 REJ domain.Contains 1 SUEL-type lectin domain.
Sequence caution: The sequence AAQ73173.1 differs from that shown. Reason: Frameshift at positions 2113 and 2117. The sequence AAQ73173.1 differs from that shown. Reason: Frameshift at positions 2114 and 2218. The sequence BAB67772.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence BAC05222.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on PKD1L2
Similar Products
Product Notes
The PKD1L2 pkd1l2 (Catalog #AAA648642) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PKD1L2 (Polycystic Kidney Disease Protein 1-like 2, PC1-like 2 Protein, Polycystin-1L2, KIAA1879, PC1L2, DKFZp686J19100, FLJ45333) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PKD1L2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the PKD1L2 pkd1l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGEDSPVAMF SWYLDNTPTE QAEPLPDACR LRGFWPRSLT LLQSNTSTLL LNSSFLQSRG EVIRIRATAL TRHAYGEDTY VISTVPPREV PACTIAPEEG TVLTSFAIFC NASTALGPLE FCFCLESGSC LHCGPEPALP SVYLPLGEEN NDFVLTVVIS ATNRAGDTQQ TQAMAKVALG DTCVEDVAFQ AAVSEKIPTA LQGEGGPEQL LQLAKAVSSM LNQEHESQGS GQSLSIDVRQ KVREHVLGSL SAVTTGLEDV QRVQELAEVL REVTCRSKEL TPSAQGSCMG DSWEGAPPAA HVSHAR. It is sometimes possible for the material contained within the vial of "PKD1L2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.