Testing Data
(Detection limit for recombinant GST tagged NCOA6IP is ~0.3ng/ml as a capture antibody.)
Mouse anti-Human PIPMT Monoclonal Antibody | anti-TGS1 antibody
PIPMT (Cap-specific Guanine-N2 Methyltransferase, Nuclear Receptor Coactivator 6-interacting Protein, PRIP-interacting Protein With Methyltransferase Motif, PIMT, Trimethylguanosine Synthase, CLL-associated Antigen KW-2, Hepatocellular Carcinoma-associate
Gene Names
TGS1; PIMT; PIPMT; NCOA6IP
Reactivity
Human
Applications
ELISA
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
PIPMT; Monoclonal Antibody; PIPMT (Cap-specific Guanine-N2 Methyltransferase; Nuclear Receptor Coactivator 6-interacting Protein; PRIP-interacting Protein With Methyltransferase Motif; PIMT; Trimethylguanosine Synthase; CLL-associated Antigen KW-2; Hepatocellular Carcinoma-associate; Anti -PIPMT (Cap-specific Guanine-N2 Methyltransferase; anti-TGS1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
3F1
Specificity
Recognizes human NCOA6IP.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MRVIAIDIDPVKIALARNNAEVYGIADKIEFICGDFLLLASFLKADVVFLSPPWGGPDYATAETFDIRTMMSPDGFEIFRLSKKITNNIVYFLPRNADIDQVASLAGPGGQVEIEQNFLNNKLKTITAYFGDLIRRPASET
Applicable Applications for anti-TGS1 antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Immunogen
Full length recombinant corresponding to aa1-142 from human NCOA6IP (AAH11999) with GST tag. MW of the GST tag alone is 26kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(Detection limit for recombinant GST tagged NCOA6IP is ~0.3ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged NCOA6IP is ~0.3ng/ml as a capture antibody.)
Related Product Information for anti-TGS1 antibody
The nuclear receptor coactivators participate in the transcriptional activation of specific genes by nuclear receptors. Using a coactivator peroxisome proliferator-activated receptor-interacting protein (PRIP) as bait, a novel, protein has been identified, designated PRIP-interacting protein with methyltransferase domain (PIMT). It is expressed in heart, skeletal muscle, kidney, liver, and placenta and is a component of nuclear receptor signal transduction apparatus acting through PRIP.
Product Categories/Family for anti-TGS1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
96,620 Da
NCBI Official Full Name
trimethylguanosine synthase isoform X1
NCBI Official Synonym Full Names
trimethylguanosine synthase 1
NCBI Official Symbol
TGS1
NCBI Official Synonym Symbols
PIMT; PIPMT; NCOA6IP
NCBI Protein Information
trimethylguanosine synthase; SEREX-defined; CLL-associated antigen KW-2; PRIP-interacting protein PIPMT; trimethylguanosine synthase homolog; cap-specific guanine-N2 methyltransferase; hepatocellular carcinoma-associated antigen 137; nuclear receptor coactivator 6 interacting protein; nuclear receptor coactivator 6-interacting protein; PRIP-interacting protein with methyltransferase motif; PRIP-interacting protein with methyltransferase domain
UniProt Protein Name
Trimethylguanosine synthase
Protein Family
UniProt Gene Name
TGS1
UniProt Synonym Gene Names
HCA137; NCOA6IP; PIMT; PIMT; PIPMT
UniProt Entry Name
TGS1_HUMAN
Uniprot Description
PIMT: a nuclear protein and apparent methyltransferase. Binds S-adenosyl-L-methionine and RNA. Plays a role in transcriptional regulation. Interacts with NCOA, CBP, p300, and PPARBP. Ubiquitously expressed. High expression in heart, skeletal muscle, kidney, liver and placenta.
Protein type: Methyltransferase; Nuclear receptor co-regulator; EC 2.1.1.-; RNA processing
Chromosomal Location of Human Ortholog: 8q11
Cellular Component: small nuclear ribonucleoprotein complex; nucleoplasm; Cajal body; extracellular space; cytoplasm; nucleus; cytosol
Molecular Function: protein binding
Biological Process: spliceosomal snRNP biogenesis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; ribonucleoprotein complex biogenesis and assembly; RNA capping; gene expression; cellular lipid metabolic process
Research Articles on TGS1
Similar Products
Product Notes
The TGS1 tgs1 (Catalog #AAA642074) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PIPMT (Cap-specific Guanine-N2 Methyltransferase, Nuclear Receptor Coactivator 6-interacting Protein, PRIP-interacting Protein With Methyltransferase Motif, PIMT, Trimethylguanosine Synthase, CLL-associated Antigen KW-2, Hepatocellular Carcinoma-associate reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIPMT can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Researchers should empirically determine the suitability of the TGS1 tgs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MRVIAIDIDP VKIALARNNA EVYGIADKIE FICGDFLLLA SFLKADVVFL SPPWGGPDYA TAETFDIRTM MSPDGFEIFR LSKKITNNIV YFLPRNADID QVASLAGPGG QVEIEQNFLN NKLKTITAYF GDLIRRPASE T. It is sometimes possible for the material contained within the vial of "PIPMT, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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