Testing Data
(Detection limit for recombinant GST tagged PIGW is 0.3 ng/ml as a capture antibody.)
Mouse PIGW Monoclonal Antibody | anti-PIGW antibody
PIGW (Phosphatidylinositol Glycan Anchor Biosynthesis, Class W, FLJ37433, Gwt1) (Biotin)
Testing Data
(Detection limit for recombinant GST tagged PIGW is 0.3 ng/ml as a capture antibody.)
Testing Data
(Detection limit for recombinant GST tagged PIGW is 0.3 ng/ml as a capture antibody.)
Western Blot (WB)
(PIGW monoclonal antibody (M05), clone 1D8. Western Blot analysis of PIGW expression in MCF-7.)
Western Blot (WB)
(PIGW monoclonal antibody (M05), clone 1D8. Western Blot analysis of PIGW expression in MCF-7.)
NCBI and Uniprot Product Information
NCBI Description
Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).[supplied by OMIM, Mar 2008]
Uniprot Description
PIGW: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. Belongs to the PIGW family.
Protein type: EC 2.3.-.-; Endoplasmic reticulum; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 17q12
Cellular Component: endoplasmic reticulum membrane; integral component of membrane
Molecular Function: O-acyltransferase activity
Biological Process: GPI anchor metabolic process; preassembly of GPI anchor in ER membrane
Disease: Hyperphosphatasia With Mental Retardation Syndrome 5
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Product Notes
The PIGW pigw (Catalog #AAA6174652) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PIGW can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PIGW pigw for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGW, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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