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Testing Data (Mouse anti peroxiredoxin 2 antibody IHC staining of human cancerous endometrial tissue (formalin fixed, paraffin embedded))

Mouse anti-Human PEROXIREDOXIN 2 Monoclonal Antibody | anti-PRDX2 antibody

MOUSE ANTI PEROXIREDOXIN 2

Gene Names
PRDX2; PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
PEROXIREDOXIN 2; Monoclonal Antibody; MOUSE ANTI PEROXIREDOXIN 2; anti-PRDX2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1E8
Specificity
PEROXIREDOXIN 2
Form/Format
Purified IgG - liquid
Concentration
IgG concentration 1.0 mg/ml (varies by lot)
Sequence Length
198
Applicable Applications for anti-PRDX2 antibody
ELISA, Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
Western Blot: 1/2000; 1/4000
Reactivity Notes
Mouse, Rat
Preparation
IgG fraction prepared by ammonium sulphate precipitation
Preservative Stabilisers
0.03% Sodium Azide (NaN3), 0.01% Bovine Serum Albumin, 50% Glycerol
Buffer Solution
HEPES buffered saline
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 12 months from date of despatch

Testing Data

(Mouse anti peroxiredoxin 2 antibody IHC staining of human cancerous endometrial tissue (formalin fixed, paraffin embedded))

Testing Data (Mouse anti peroxiredoxin 2 antibody IHC staining of human cancerous endometrial tissue (formalin fixed, paraffin embedded))

Testing Data

(Mouse anti peroxiredoxin 2 antibody IHC staining of normal human endometrial tissue (formalin fixed, paraffin embedded))

Testing Data (Mouse anti peroxiredoxin 2 antibody IHC staining of normal human endometrial tissue (formalin fixed, paraffin embedded))

Testing Data

(Mouse anti peroxiredoxin 2 antibody IHC staining of normal human kidney tissue (formalin fixed, paraffin embedded))

Testing Data (Mouse anti peroxiredoxin 2 antibody IHC staining of normal human kidney tissue (formalin fixed, paraffin embedded))

Testing Data

(Mouse anti peroxiredoxin 2 antibody recognizes a band of approximately 26 kDa in HeLa (lane 1), 293T (lane 2), SH-SY5Y (lane 3) and HepG2 (lane 4) cell lysates)

Testing Data (Mouse anti peroxiredoxin 2 antibody recognizes a band of approximately 26 kDa in HeLa (lane 1), 293T (lane 2), SH-SY5Y (lane 3) and HepG2 (lane 4) cell lysates)
Related Product Information for anti-PRDX2 antibody
Mouse anti peroxiredoxin 2 antibody, clone 1E8, recognizes peroxiredoxin 2 also known as natural killer cell-enhancing factor B, thiol-specific antioxidant protein and thioredoxin peroxidase 1. Peroxiredoxin 2 is a cytoplasmic enzyme involved in cellular redox regulation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
15,819 Da
NCBI Official Full Name
Peroxiredoxin-2
NCBI Official Synonym Full Names
peroxiredoxin 2
NCBI Official Symbol
PRDX2
NCBI Official Synonym Symbols
PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a
NCBI Protein Information
peroxiredoxin-2
UniProt Protein Name
Peroxiredoxin-2
Protein Family
UniProt Gene Name
PRDX2
UniProt Synonym Gene Names
NKEFB; TDPX1; NKEF-B; TSA
UniProt Entry Name
PRDX2_HUMAN

NCBI Description

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]

Uniprot Description

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.

Research Articles on PRDX2

Similar Products

Product Notes

The PRDX2 prdx2 (Catalog #AAA224831) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MOUSE ANTI PEROXIREDOXIN 2 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEROXIREDOXIN 2 can be used in a range of immunoassay formats including, but not limited to, ELISA, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). Western Blot: 1/2000; 1/4000. Researchers should empirically determine the suitability of the PRDX2 prdx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEROXIREDOXIN 2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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