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Mouse anti-PAP 100% PAP Monoclonal Antibody | anti-PAP antibody

PAP antibody

Gene Names
ACPP; ACP3; 5'-NT; ACP-3
Reactivity
PAP 100%
Applications
ELISA
Synonyms
PAP; Monoclonal Antibody; PAP antibody; Monoclonal PAP; Anti-PAP; Prostatic Acid Phosphatase; Anti PAP; anti-PAP antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
PAP 100%
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M01010921
Specificity
Human PAP
Form/Format
Purified mouse ascites by Protein A affinity chromatography, supplied in PBS buffer, pH 7.5, with 0.1% sodium azide.
Concentration
2.2 mg/mL (varies by lot)
Sequence Length
386
Applicable Applications for anti-PAP antibody
ELISA (EIA)
Application Notes
Matched pair antibody available for PAP antibody: MBS530241
Immunogen
Higly pure human PAP.
Additional Remarks
This clone is excellent for ELISA and IRMA.
Affinity Constant
1 x 109 L/M
Biological Significance
Prostatic acid phosphatase (PAP), also prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. It may be found in increased amounts in men who have prostate cancer or other diseases. The highest levels of acid phosphatase are found in metastasized prostate cancer.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Preparation and Storage
Store at 4°C.
Related Product Information for anti-PAP antibody
Mouse monoclonal PAP antibody
Product Categories/Family for anti-PAP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
55
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
prostatic acid phosphatase isoform PAP
NCBI Official Synonym Full Names
acid phosphatase, prostate
NCBI Official Symbol
ACPP
NCBI Official Synonym Symbols
ACP3; 5'-NT; ACP-3
NCBI Protein Information
prostatic acid phosphatase
UniProt Protein Name
Prostatic acid phosphatase
Protein Family
UniProt Gene Name
ACPP
UniProt Synonym Gene Names
PAP; 5'-NT; TMPase
UniProt Entry Name
PPAP_HUMAN

NCBI Description

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq, Sep 2008]

Uniprot Description

ACPP: A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; EC 3.1.3.2; Phosphatase; EC 3.1.3.5; Cofactor and Vitamin Metabolism - riboflavin

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: multivesicular body; extracellular space; Golgi cisterna; lysosomal membrane; apical part of cell; integral to membrane; plasma membrane; vesicle membrane; intracellular; nucleus; filopodium; secretory granule

Molecular Function: 5'-nucleotidase activity; choline binding; identical protein binding; acid phosphatase activity; protein homodimerization activity; phosphoric monoester hydrolase activity; thiamin phosphate phosphatase activity

Biological Process: thiamin metabolic process; dephosphorylation; positive regulation of adenosine receptor signaling pathway; nucleotide metabolic process; regulation of sensory perception of pain; adenosine metabolic process; purine base metabolic process

Research Articles on PAP

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Product Notes

The PAP acpp (Catalog #AAA530305) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The PAP antibody reacts with PAP 100% and may cross-react with other species as described in the data sheet. AAA Biotech's PAP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Matched pair antibody available for PAP antibody: MBS530241. Researchers should empirically determine the suitability of the PAP acpp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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