Mouse p53, dimethylated Monoclonal Antibody
p53, dimethylated (Tumor Suppressor Protein, Oncogene Protein)
Applications
ELISA
Purity
Affinity PurifiedPurified by Protein G affinity chromatography.
Synonyms
p53; dimethylated; Monoclonal Antibody; dimethylated (Tumor Suppressor Protein; Oncogene Protein); Anti -p53; anti-p53; dimethylated antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9F634
Specificity
Recognizes dimethylated p53 (K372)
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Applicable Applications for anti-p53, dimethylated antibody
ELISA (EL/EIA)
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 1:1000
Dilution: ELISA: 1:1000
Immunogen
KLH-conjugated synthetic peptide SHLKS [dimethyl-K]KGQST corresponding to aa367-377 of human tumor suppressor p53
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-p53, dimethylated antibody
The C terminus of p53 is rich in lysines, which are subjected to different modifications to regulate p53 activity. p53 tumor suppressor gene mutations are one of the most common genetic alterations in human tumors, including lymphomas. Altering or inactivating p53 by mutation or reaction with oncogenes or viruses may cause depletion of p53, or conversion of p53 from a tumor suppressor gene to a transforming oncogene. The nuclear protein p53 is associated with cell transformation and proliferation, with definitive possibilities as a marker in malignant lymphoma progression. p53's role in the multistep process leading to cancer is still being investigated, with an emphasis on its relation and control over additional tumor suppressors.
Product Categories/Family for anti-p53, dimethylated antibody
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Product Notes
The p53, dimethylated (Catalog #AAA605651) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's p53, dimethylated can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA. Dilution: ELISA: 1:1000. Researchers should empirically determine the suitability of the p53, dimethylated for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p53, dimethylated, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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