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Testing Data (Staining of mouse thymocytes with N5375-03Q.)

Mouse anti-Human, Mouse NOTCH 1 Monoclonal Antibody | anti-NOTCH 1 antibody

NOTCH 1 (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300, Motch, Notch1) (HRP)

Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
NOTCH 1; Monoclonal Antibody; NOTCH 1 (Neurogenic Locus Notch Homolog Protein 1; Motch A; mT14; p300; Motch; Notch1) (HRP); anti-NOTCH 1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10F238
Specificity
Recognizes mouse NOTCH 1. Species Crossreactivity: human.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Applicable Applications for anti-NOTCH 1 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Synthetic peptide corresponding to cdc10-NCR region within mouse Notch1.
Conjugate
HRP
Preparation and Storage
Store at -20 degree C.

Testing Data

(Staining of mouse thymocytes with N5375-03Q.)

Testing Data (Staining of mouse thymocytes with N5375-03Q.)

Testing Data

(Staining of mouse thymocytes with N5375-03S.)

Testing Data (Staining of mouse thymocytes with N5375-03S.)

Testing Data

(Staining of mouse thymocytes with N5375-03T.)

Testing Data (Staining of mouse thymocytes with N5375-03T.)
Product Categories/Family for anti-NOTCH 1 antibody
References
1. Ray, W.J. et al. (1999) Evidence for a physical interaction between presenilin and Notch. Proc. Natl. Acad. Sci. USA. 96:3263-3268. 2. Huppert, S.S. et al. (2000) Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1. Nature 405: 966-970. 3. Espinosa, L. et al. (2002) p65-NFkappa B synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR. J. Cell. Sci. 115: 1295-1303. 4. Kang-Decker, N. et al. (2004) Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency. Cancer Cell. 5: 177-189.

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Product Notes

The NOTCH 1 (Catalog #AAA6251129) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NOTCH 1 (Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300, Motch, Notch1) (HRP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NOTCH 1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the NOTCH 1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOTCH 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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