Mouse anti-Human Non-Metastatic Cells 1 Monoclonal Antibody | anti-NME1 antibody
Mouse Anti Human Non-Metastatic Cells 1
Reactivity
Human
Applications
ELISA, Western Blot, Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence
Purity
Purified from mouse ascitic fluids by protein-A affinity chromatography
Synonyms
Non-Metastatic Cells 1; Monoclonal Antibody; Mouse Anti Human Non-Metastatic Cells 1; Nucleoside diphosphate kinase A; NDP kinase A; NDK A; Tumor metastatic process-associated protein; Metastasis inhibition factor nm23; nm23-H1; Granzyme A-activated DNase; GAAD; NME1; NDPKA; NM23; NB; AWD; NBS; NDPK-A; NME1 Antibody; Mouse Anti Human; anti-NME1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b heavy chain and k light chain
Clone Number
PAT5F4AT
Purity/Purification
Purified from mouse ascitic fluids by protein-A affinity chromatography
Form/Format
Sterile filtered colorless solution
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide
1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide
Applicable Applications for anti-NME1 antibody
ELISA (EIA), Western Blot (WB), Flow cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Immunogen
Anti-human NME1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NME1 amino acids 1-152 purified from E Coli
Preparation and Storage
For periods up to 1 month store at 4 degree C, for longer periods of time, store at-20 degree C.
Prevent freeze thaw cycles
Prevent freeze thaw cycles
Related Product Information for anti-NME1 antibody
NDK (Nucleoside diphosphate kinase) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by NME2) isoforms. NME1 is involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. It also has tumor metastasis-suppressive capacity. NME1 has a key role in the synthesis of nucleoside triphosphates other than ATP. NME1 is essential for neural development including neural patterning and cell future determination. The NME1 gene is expressed in various tumor types where its levels have been alternatively linked to reduced or increased metastatic potential. Decrease in NME1 expression is notably connected to aggressive behavior in melanoma, breast, colon, and gastric carcinomas. In contrast, elevated levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas.Somatic mutations of the NME1 gene are found in neuroblastoma. Increased NME1 in neuroblastoma is linked to features of the disease that are associated with aggressive tumors.
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Product Notes
The NME1 (Catalog #AAA146986) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Non-Metastatic Cells 1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Non-Metastatic Cells 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Flow cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the NME1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Non-Metastatic Cells 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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