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Mouse Neurocan Monoclonal Antibody | anti-NCAN antibody

Mouse Anti-Neurocan [650.24]

Gene Names
NCAN; CSPG3
Applications
Western Blot, Immunocytochemistry, Immunofluorescence
Purity
Protein G
Synonyms
Neurocan; Monoclonal Antibody; Mouse Anti-Neurocan [650.24]; Chondroitin sulfate proteoglycan 3 antibody; Cspg3 antibody; NCAN antibody; NEUR antibody; Neurocan coreprotein antibody; Neurocan antibody; anti-NCAN antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
650.24
Specificity
Neurocan core protein, also reacts with nuerocan C fragment
Purity/Purification
Protein G
Form/Format
Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-NCAN antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes
Optimal antibody dilution should be determined by titration.
Immunogen
Embryonic rat brain proteoglycans
Myeloma/fusion partners
P3X myeloma
Preparation and Storage
Store at +4°C for one month, or in small aliquots at -20°C for longer periods. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
neurocan core protein
NCBI Official Synonym Full Names
neurocan
NCBI Official Symbol
NCAN
NCBI Official Synonym Symbols
CSPG3
NCBI Protein Information
neurocan core protein; chondroitin sulfate proteoglycan 3 (neurocan); neurocan proteoglycan
UniProt Protein Name
Neurocan core protein
Protein Family
UniProt Gene Name
NCAN
UniProt Synonym Gene Names
CSPG3; NEUR
UniProt Entry Name
NCAN_HUMAN

NCBI Description

Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]

Uniprot Description

CSPG3: May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid. Belongs to the aggrecan/versican proteoglycan family.

Protein type: Secreted, signal peptide; Secreted; Cell adhesion

Chromosomal Location of Human Ortholog: 19p12

Cellular Component: lysosomal lumen; proteinaceous extracellular matrix; Golgi lumen; extracellular region

Molecular Function: extracellular matrix structural constituent; hyaluronic acid binding; calcium ion binding; carbohydrate binding

Biological Process: chondroitin sulfate metabolic process; axon guidance; extracellular matrix organization and biogenesis; central nervous system development; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; chondroitin sulfate catabolic process; regulation of synapse structural plasticity; pathogenesis; cell adhesion; skeletal development; dermatan sulfate biosynthetic process

Research Articles on NCAN

Similar Products

Product Notes

The NCAN ncan (Catalog #AAA375211) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Neurocan can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF). Optimal antibody dilution should be determined by titration. Researchers should empirically determine the suitability of the NCAN ncan for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurocan, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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