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Western Blot (WB) (Western Blot analysis of Human skeletal muscle tissue using Myosin 2a Monoclonal Antibody at dilution of 1:4000)

Mouse anti-Human MYH2 Monoclonal Antibody | anti-MYH2 antibody

MYH2 Monoclonal Antibody

Gene Names
MYH2; IBM3; MYH2A; MYPOP; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Protein A purification
Synonyms
MYH2; Monoclonal Antibody; MYH2 Monoclonal Antibody; adult 2; Fast 2a myosin heavy chain; IBM3; Inclusion body myopathy 3; autosomal dominant; MYH2A; MYHas8; MyHC IIa; MyHC-2a; MyHC-IIa; MYHSA2; Myosin heavy chain 2; Myosin heavy chain 2a; Myosin heavy chain; Myosin heavy chain IIa; Myosin heavy chain skeletal muscle adult 2; Myosin heavy polypeptide 2 skeletal muscle adult; Myosin-2; MYPOP; skeletal muscle; Type IIA myosin heavy chain; Myosin 2a; anti-MYH2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
47
Purity/Purification
Protein A purification
Concentration
1mg/mL (varies by lot)
Sequence Length
1941
Applicable Applications for anti-MYH2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:1000-1:10000
IHC: 1:20-1:200
Immunogen
Synthetic Peptide
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Human skeletal muscle tissue using Myosin 2a Monoclonal Antibody at dilution of 1:4000)

Western Blot (WB) (Western Blot analysis of Human skeletal muscle tissue using Myosin 2a Monoclonal Antibody at dilution of 1:4000)
Related Product Information for anti-MYH2 antibody
MYH2 (Myosin II) is a member of the class II or conventional myosin heavy chains. Myosin II was first isolated from muscle but is also found in non muscle cells, and it is especially enriched in highly motile cell types such as amoebae. It forms bipolar filaments that interact with actin filaments to produce contraction. And it is the motor protein that generates force to drive muscle contraction. Functions in skeletal muscle contraction. The antibody is specific to MYH2, will not bind other myosins.
Product Categories/Family for anti-MYH2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated: 223kDa
Observed: 200kDa
NCBI Official Full Name
myosin-2
NCBI Official Synonym Full Names
myosin heavy chain 2
NCBI Official Symbol
MYH2
NCBI Official Synonym Symbols
IBM3; MYH2A; MYPOP; MYHSA2; MYHas8; MyHC-2A; MyHC-IIa
NCBI Protein Information
myosin-2
UniProt Protein Name
Myosin-2
UniProt Gene Name
MYH2
UniProt Synonym Gene Names
MYHSA2; MyHC-2a; MyHC-IIa

NCBI Description

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2009]

Uniprot Description

Muscle contraction. Required for cytoskeleton organization ().

Research Articles on MYH2

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Product Notes

The MYH2 myh2 (Catalog #AAA2541990) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MYH2 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:1000-1:10000 IHC: 1:20-1:200. Researchers should empirically determine the suitability of the MYH2 myh2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYH2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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