Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant MTRF1L protein using MTRF1L antibody)
Mouse MTRF1L Monoclonal Antibody | anti-MTRF1L antibody
MTRF1L antibody
IHC: 1:50
WB: 1:1000
Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant MTRF1L protein using MTRF1L antibody)
Immunofluorescence (IF)
(Immunofluorescent staining of COS7 cells transiently transfected with recombinant MTRF1L protein using MTRF1L antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MTRF1L protein (Right) or empty vector (Left) detected with MTRF1L antibody)
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant MTRF1L protein (Right) or empty vector (Left) detected with MTRF1L antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of MTRF1L protein in paraffin embedded Human liver tissue using MTRF1L antibody)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of MTRF1L protein in paraffin embedded Human liver tissue using MTRF1L antibody)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Uniprot Description
MTRF1L: Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG. Belongs to the prokaryotic/mitochondrial release factor family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation
Chromosomal Location of Human Ortholog: 6q25-q26
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: translation release factor activity, codon specific
Biological Process: mitochondrial translation; organelle organization and biogenesis
Research Articles on MTRF1L
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Product Notes
The MTRF1L mtrf1l (Catalog #AAA834065) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MTRF1L can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB). IF: 1:100 IHC: 1:50 WB: 1:1000. Researchers should empirically determine the suitability of the MTRF1L mtrf1l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTRF1L, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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