Testing Data
(Immunocytochemistry stain of Hela using MPI antibody (1:300).)
Mouse anti-Human, Rat MPI (Mannose Phosphate Isomerase) Monoclonal Antibody | anti-MPI antibody
MPI (Mannose Phosphate Isomerase) Antibody
Gene Names
MPI; PMI; PMI1; CDG1B
Reactivity
Human, Rat
Applications
Western Blot, Immunocytochemistry
Purity
Affinity purified
Synonyms
MPI (Mannose Phosphate Isomerase); Monoclonal Antibody; MPI (Mannose Phosphate Isomerase) Antibody; Phosphohexomutase; Phosphomannose isomerase; anti-MPI antibody
Host
Mouse
Reactivity
Human, Rat
Clonality
Monoclonal
Isotype
IgG1
Specificity
This antibody detects endogenous levels of MPI and does not cross-react with related proteins.
Purity/Purification
Affinity purified
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Sequence Length
373
Applicable Applications for anti-MPI antibody
Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Purified recombinant human MPI protein fragments expressed in E Coli.
Cellular Localization
Cytoplasm
Testing Data
(Immunocytochemistry stain of Hela using MPI antibody (1:300).)
Testing Data
(Immunocytochemistry stain of Hela using MPI antibody (1:300).)
Testing Data #2
(Western blot detection of MPI in Rat kidney,Rat brain, A549&LNCAP cell lysates and using MPI antibody (1:1000 diluted). Predicted band size: 54KDa Observed band size: 45KDa.)
Testing Data #2
(Western blot detection of MPI in Rat kidney,Rat brain, A549&LNCAP cell lysates and using MPI antibody (1:1000 diluted). Predicted band size: 54KDa Observed band size: 45KDa.)
Related Product Information for anti-MPI antibody
UniPort Summary Function: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Entrez Summary: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
Entrez Summary: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.
Product Categories/Family for anti-MPI antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54kDa
NCBI Official Full Name
mannose-6-phosphate isomerase isoform 3
NCBI Official Synonym Full Names
mannose phosphate isomerase
NCBI Official Symbol
MPI
NCBI Official Synonym Symbols
PMI; PMI1; CDG1B
NCBI Protein Information
mannose-6-phosphate isomerase
UniProt Protein Name
Mannose-6-phosphate isomerase
Protein Family
UniProt Gene Name
MPI
UniProt Synonym Gene Names
PMI1; PMI
NCBI Description
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Research Articles on MPI
Similar Products
Product Notes
The MPI mpi (Catalog #AAA857936) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MPI (Mannose Phosphate Isomerase) Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MPI (Mannose Phosphate Isomerase) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the MPI mpi for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPI (Mannose Phosphate Isomerase), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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