Western Blot (WB)
(Western blot detection of Moesin in COS7, Jurkat, HaCat and Hela cell lysates using Moesin mouse mAb (dilution 1:1000).Predicted band size:67.8KDa.Observed band size:67.8KDa.)
Moesin Monoclonal Antibody | anti-MSN antibody
Anti-Moesin Mouse mAb
Gene Names
MSN; HEL70; IMD50
Reactivity
Human, Monkey
Applications
Western Blot
Purity
Affinity Purified
Synonyms
Moesin; Monoclonal Antibody; Anti-Moesin Mouse mAb; Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin/anaplastic lymphoma kinase fusion protein; Msn; MSN/ALK fusion; anti-MSN antibody
Host
Mouse
Source: Human
Source: Human
Reactivity
Human, Monkey
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2C12-D10-F1
Purity/Purification
Affinity Purified
Form/Format
Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
Concentration
1mg/ml (varies by lot)
Sequence Length
577
Applicable Applications for anti-MSN antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
Purified recombinant fragment of human Moesin expressed in E Coli.
Sensitivity
The antibody detects endogenous level of total Moesin protein.
Sequence Similarities
Contains 1 FERM domain.
Subunit Structure
In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation. Binds SLC9A3R1. Interacts with PPP1R16B. Interacts with PDZD8. Interacts with SELPLG and SYK; mediates the activation of SYK by SELPLG.
Subcellular Location
Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphory
Western Blot (WB)
(Western blot detection of Moesin in COS7, Jurkat, HaCat and Hela cell lysates using Moesin mouse mAb (dilution 1:1000).Predicted band size:67.8KDa.Observed band size:67.8KDa.)
Western Blot (WB)
(Western blot detection of Moesin in COS7, Jurkat, HaCat and Hela cell lysates using Moesin mouse mAb (dilution 1:1000).Predicted band size:67.8KDa.Observed band size:67.8KDa.)
Related Product Information for anti-MSN antibody
Entrez Summary: Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
UniPort Summary Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
UniPort Summary Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Product Categories/Family for anti-MSN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
67.8
NCBI Official Full Name
moesin
NCBI Official Synonym Full Names
moesin
NCBI Official Symbol
MSN
NCBI Official Synonym Symbols
HEL70; IMD50
NCBI Protein Information
moesin
UniProt Protein Name
Moesin
Protein Family
UniProt Gene Name
MSN
NCBI Description
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
Uniprot Description
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Research Articles on MSN
Similar Products
Product Notes
The MSN msn (Catalog #AAA475625) is an Antibody produced from Mouse Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti-Moesin Mouse mAb reacts with Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's Moesin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the MSN msn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Moesin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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