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Testing Data (TD)

Mouse anti-Human MGO-modified proteins Monoclonal Antibody

MGO-modified proteins, Human, mAb MGO-1

Reactivity
Human
Applications
Western Blot
Purity
Protein G
Synonyms
MGO-modified proteins; Monoclonal Antibody; Human; mAb MGO-1; anti-MGO-modified proteins antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Purity/Purification
Protein G
Form/Format
0.2 um filtered in PBS+0.1%BSA+0.02%NaN3
Concentration
0.81 mg/mL (varies by lot)
Applicable Applications for anti-MGO-modified proteins antibody
Immunoassay (IA), P, Western Blot (WB)
Application Notes
Application Use: For immunohistochemistry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.
Immunogen
MGO-modified KLH
Volume
1 mL
Cross-Reactivity
Multispecies: Yes
Glyoxal-modified albumin: No
3-Deoxyglucosone-modified albumin: No
CML (Carboxy Methyl Lysine): No
Pentosidine: No
Endotoxin
0.07 EU/mg
Preparation and Storage
Product should be stored at 4 degree C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.

Testing Data (TD)

Testing Data (TD)
Related Product Information for anti-MGO-modified proteins antibody
Product Description: The monoclonal antibody MGO-1recognizes human MGO modified proteins. Methylglyoxal (MGO) is an endogenous product of glucose metabolism. Increased production and accumulation of methylglyoxal (MGO), as well as increased modification of proteins by glycoxidation, are hallmarks of aging and diabetes. MGO was shown to modify proteins and to contribute to the accumulation of damaged proteins that can be toxic to cells. A number of studies have shown that MGO levels are significantly elevated in patients with Type 2 Diabetes- and correlates well with fasting plasma glucose and hemoglobin A1c (HbA1c) levels. Moreover, increased formation of the MGO is implicated in renal dysfunction and is known to be involved in the development of DN (diabetic nephropathy).

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Product Notes

The MGO-modified proteins (Catalog #AAA584127) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The MGO-modified proteins, Human, mAb MGO-1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MGO-modified proteins can be used in a range of immunoassay formats including, but not limited to, Immunoassay (IA), P, Western Blot (WB). Application Use: For immunohistochemistry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting. Researchers should empirically determine the suitability of the MGO-modified proteins for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MGO-modified proteins, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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