Mouse anti-Human MGC3207 Monoclonal Antibody | anti-MGC3207 antibody

MGC3207 (Translation Initiation Factor EIF-2B Subunit Alpha/Beta/Delta-Like Protein) (Biotin)

Cat. Num. AAA6142916

• Gene Names: MRI1; M1Pi; MRDI; MTNA; Ypr118w
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MGC3207; Monoclonal Antibody; MGC3207 (Translation Initiation Factor EIF-2B Subunit Alpha/Beta/Delta-Like Protein) (Biotin); anti-MGC3207 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1,k
• Clone Number: 2D11-1G4
• Specificity: Recognizes human MGC3207.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 1747

• Applicable Applications for anti-MGC3207 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant corresponding to aa1-370 from human MGC3207 (AAH01703) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MTLEAIRYSRGSLQILDQLLLPKQSRYEAVGSVHQAWEAIRAMKVRGAPAIALVGCLSLAVELQAGAGGPGLAALVAFVRDKLSFLVTARPTAVNMARAARDLADVAAREAEREGATEEAVRERVICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTLDGPQM
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (66.7kD).)

Western Blot (WB)

(MGC3207 monoclonal antibody, Western Blot analysis of MGC3207 expression in HL-60.)

Testing Data

(Detection limit for recombinant GST tagged MGC3207 is ~0.1ng/ml as a capture antibody.)

Related Product Information for anti-MGC3207 antibody

Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

Product Categories/Family for anti-MGC3207 antibody

Antibodies; Enzymes; Isomerase

NCBI and Uniprot Product Information

• NCBI GI #: 12804572
• NCBI GeneID: 84245
• NCBI Official Full Name: Homo sapiens methylthioribose-1-phosphate isomerase homolog (S. cerevisiae), mRNA
• NCBI Official Synonym Full Names: methylthioribose-1-phosphate isomerase 1
• NCBI Official Symbol: MRI1
• NCBI Official Synonym Symbols: M1Pi; MRDI; MTNA; Ypr118w
• NCBI Protein Information: methylthioribose-1-phosphate isomerase

NCBI Description

This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). [provided by RefSeq, Jul 2016]