Mouse anti-Human MDR3 Monoclonal Antibody | anti-MDR3 antibody
SensiStain Anti-MDR3 Antibody
ELISA: 1:1000-1:2000
Expiration date is one (1) year from date of receipt.
Shipping Condition: Ice Packs
NCBI and Uniprot Product Information
Uniprot Description
ABCB4: a transporter that mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human ABCB4 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Interacts with HAX1. Defects are the cause of gallstones, and progressive familial intrahepatic cholestasis 3, an autosomal recessive liver disorder that progresses to cirrhosis and liver failure before adulthood. Two alternatively spliced human isoforms have been described.
Protein type: EC 3.6.3.44; Hydrolase; Membrane protein, integral; Transporter, ABC family; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 7q21.1
Cellular Component: intercellular canaliculus; membrane; integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: ATPase activity, coupled to transmembrane movement of substances; xenobiotic-transporting ATPase activity; ATP binding
Biological Process: response to drug; transport; xenobiotic transport; multidrug transport; lipid metabolic process; cellular lipid metabolic process; transmembrane transport
Disease: Gallbladder Disease 1; Cholestasis, Progressive Familial Intrahepatic, 3; Cholestasis, Intrahepatic, Of Pregnancy 3
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Product Notes
The MDR3 mdr3 (Catalog #AAA4160468) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SensiStain Anti-MDR3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MDR3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:1000-1:3000 ELISA: 1:1000-1:2000. Researchers should empirically determine the suitability of the MDR3 mdr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MDR3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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