Mouse MAP2 Monoclonal Antibody | anti-MAP2 antibody

MAP2(N-term) Monoclonal Antibody

Cat. Num. AAA9400434

• Gene Names: MAP2; MAP2A; MAP2B; MAP2C
• Reactivity: Human, Bovine, Mouse, Rat, Porcine
• Applications: Western Blot, Immunocytochemistry
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: MAP2; Monoclonal Antibody; MAP2(N-term) Monoclonal Antibody; microtubule-associated protein 2 MAP-2; anti-MAP2 antibody

• Host: Mouse
• Reactivity: Human, Bovine, Mouse, Rat, Porcine
• Clonality: Monoclonal
• Isotype: IgG2b
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
• Sequence Length: 559

• Applicable Applications for anti-MAP2 antibody: Western Blot (WB), Immunocytochemistry (ICC)
• Application Notes: Western blotting: 1:1000
• Immunogen Type: Recombinant protein
• Immunogen Description: Recombinant fragment, corresponding to amino acids 1636aa-1855aa of human MAP2(C-terminus).
• Target Name: MAP2
• Preparation and Storage: store at -20 degree C

Testing Data

(1:1000 dilution of this antibody detected MAP2 on 40ug of cell lysates)

Testing Data

(HeLa cells using anti- MAP2 (N-terminus) antibody diluted 1:150)

Product Categories/Family for anti-MAP2 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 87578394
• NCBI GeneID: 4133
• NCBI Accession #: NP_001034627.1
• NCBI GenBank Nucleotide #: NM_001039538.1
• UniProt Accession #: P11137; Q17S04; Q8IUX2; Q99975; Q99976
• Molecular Weight: 58,954 Da
• NCBI Official Full Name: microtubule-associated protein 2 isoform 5
• NCBI Official Synonym Full Names: microtubule-associated protein 2
• NCBI Official Symbol: MAP2
• NCBI Official Synonym Symbols: MAP2A; MAP2B; MAP2C
• NCBI Protein Information: microtubule-associated protein 2
• UniProt Protein Name: Microtubule-associated protein 2
• Protein Family: Microtubule-associated protein
• UniProt Gene Name: MAP2
• UniProt Synonym Gene Names: MAP-2
• UniProt Entry Name: MTAP2_HUMAN

NCBI Description

This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

Uniprot Description

MAP2: a member of the microtubule-associated protein (MAP) family. Its exact function is unknown but MAPs appear to stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. Expressed at high levels in neural tissue and the prostate. Four alternatively spliced transcript variants have been reported.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 2q34-q35

Cellular Component: microtubule; microtubule associated complex; cell soma; cytoplasm; nucleolus; dendritic shaft

Molecular Function: calmodulin binding; protein binding; microtubule binding; structural molecule activity

Biological Process: axonogenesis; dendrite morphogenesis; neurite development; microtubule bundle formation; central nervous system neuron development