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Rat anti-Mouse Ly6A/E (Sca-1) Monoclonal Antibody | anti-Ly6A/E antibody

Anti-Mouse Ly6A/E (Sca-1) Monoclonal Antibody (APC Conjugated) [D7]

Gene Names
Ly6a; TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
Ly6A/E (Sca-1); Monoclonal Antibody; Anti-Mouse Ly6A/E (Sca-1) Monoclonal Antibody (APC Conjugated) [D7]; Mouse Ly6A/E(Sca-1); Ly6a; Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP; anti-Ly6A/E antibody
Ordering
For Research Use Only!
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a, kappa
Clone Number
D7
Form/Format
PBS with 0.05% Proclin300, 1% BSA
Concentration
0.5 mg/mL (varies by lot)
Sequence Length
134
Applicable Applications for anti-Ly6A/E antibody
Flow Cytometry (FC/FACS)
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 2 ug per 106 cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Conjugation
APC
Isotype Control
Rat IgG2a, kappa Isotype Control (APC Conjugated)
Preparation and Storage
Store at 2-8 degree C and protect from prolonged exposure to light. Do not freeze.
Related Product Information for anti-Ly6A/E antibody
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
lymphocyte antigen 6A-2/6E-1
NCBI Official Synonym Full Names
lymphocyte antigen 6 complex, locus A
NCBI Official Symbol
Ly6a
NCBI Official Synonym Symbols
TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
NCBI Protein Information
lymphocyte antigen 6A-2/6E-1
UniProt Protein Name
Lymphocyte antigen 6A-2/6E-1
UniProt Gene Name
Ly6a
UniProt Synonym Gene Names
Ly6; Ly-6A.2/Ly-6E.1; SCA-1; TAP
UniProt Entry Name
LY6A_MOUSE

Uniprot Description

Ly6A: T-cell activation.

Protein type: Cell surface

Cellular Component: membrane; plasma membrane; intracellular; external side of plasma membrane

Research Articles on Ly6A/E

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Product Notes

The Ly6A/E ly6a (Catalog #AAA2559403) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse Ly6A/E (Sca-1) Monoclonal Antibody (APC Conjugated) [D7] reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Ly6A/E (Sca-1) can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 2 ug per 106 cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Researchers should empirically determine the suitability of the Ly6A/E ly6a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ly6A/E (Sca-1), Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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