Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Mouse anti-Human LILRB1 Monoclonal Antibody | anti-LILRB1 antibody
Anti-LILRB1 Antibody (PE), Mouse Monoclonal
Gene Names
LILRB1; ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B
Reactivity
Human
Applications
Flow Cytometry, Functional Assay
Purity
Protein A
Synonyms
LILRB1; Monoclonal Antibody; Anti-LILRB1 Antibody (PE); Mouse Monoclonal; LILRB1 Antibody (PE); Mouse MAb; leukocyte immunoglobulin like receptor B1; Anti-CD85j Antibody; Anti-ILT-2 Antibody; Anti-ILT2 Antibody; Anti-LIR-1 Antibody; Anti-LIR1 Antibody; Anti-MIR-7 Antibody; Anti-MIR7 Antibody; Anti-XXbac-BCX85G21.4 Antibody; anti-LILRB1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
Mouse IgG1
Clone Number
06
Specificity
Human CD85/ILT2/ILR1
Purity/Purification
Protein A
Form/Format
Liquid; Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Concentration
10ul/Test, 0.1mg/ml (varies by lot)
Applicable Applications for anti-LILRB1 antibody
Flow Cytometry (FC/FACS/FCM)
Immunogen
Recombinant Human CD85/ILT2/ILR1 protein
Conjugation
PE
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD85/ILT2/ILR1 (rh CD85/ILT2/ILR1) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Preparation and Storage
This antibody can be stored at 2-8 degree C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of Human LILRB1(CD85j) expression on human peripheral blood monocytes. Cells were stained with PE-conjugated Mouse anti-Human LILRB1(CD85j). The histogram were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.)
Related Product Information for anti-LILRB1 antibody
LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia.
Product Categories/Family for anti-LILRB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
49,356 Da
NCBI Official Full Name
LIR-1
NCBI Official Synonym Full Names
leukocyte immunoglobulin like receptor B1
NCBI Official Symbol
LILRB1
NCBI Official Synonym Symbols
ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily B member 1
Protein Family
NCBI Description
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Articles on LILRB1
Similar Products
Product Notes
The LILRB1 (Catalog #AAA8107689) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-LILRB1 Antibody (PE), Mouse Monoclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LILRB1 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS/FCM). Researchers should empirically determine the suitability of the LILRB1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LILRB1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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