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Mouse anti-Human Leukocyte Immunoglobulin-like Receptor 1 Monoclonal Antibody | anti-LIR1 antibody

Leukocyte Immunoglobulin-like Receptor 1 (Leukocyte Immunoglobulin-like Receptor Subfamily B Member 1, LILRB1, LIR1, LIR-1, CD85 Antigen-like Family Member J, CD85j, CD85, FLJ37515, Immunoglobulin-like Transcript 2, ILT2, ILT-2, Monocyte/macrophage Immuno

Gene Names
LILRB1; ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B
Reactivity
Human
Applications
Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
Leukocyte Immunoglobulin-like Receptor 1; Monoclonal Antibody; Leukocyte Immunoglobulin-like Receptor 1 (Leukocyte Immunoglobulin-like Receptor Subfamily B Member 1; LILRB1; LIR1; LIR-1; CD85 Antigen-like Family Member J; CD85j; CD85; FLJ37515; Immunoglobulin-like Transcript 2; ILT2; ILT-2; Monocyte/macrophage Immuno; anti-LIR1 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
11C373
Specificity
Recognizes human LILRB1.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Sequence Length
650
Applicable Applications for anti-LIR1 antibody
FLISA, Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Applications are based on unconjugated antibody.
Immunogen
Full length recombinant protein corresponding to aa1-523, AAH15731, of human LILRB1 with GST tag. Molecular weight of the GST tag alone is 26kD.
Conjugate
MaxLight650
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Product Categories/Family for anti-LIR1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
70819
NCBI Official Full Name
Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
NCBI Official Synonym Full Names
leukocyte immunoglobulin like receptor B1
NCBI Official Symbol
LILRB1
NCBI Official Synonym Symbols
ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B
NCBI Protein Information
leukocyte immunoglobulin-like receptor subfamily B member 1
Protein Family

NCBI Description

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Research Articles on LIR1

Similar Products

Product Notes

The LIR1 (Catalog #AAA6220468) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Leukocyte Immunoglobulin-like Receptor 1 (Leukocyte Immunoglobulin-like Receptor Subfamily B Member 1, LILRB1, LIR1, LIR-1, CD85 Antigen-like Family Member J, CD85j, CD85, FLJ37515, Immunoglobulin-like Transcript 2, ILT2, ILT-2, Monocyte/macrophage Immuno reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Leukocyte Immunoglobulin-like Receptor 1 can be used in a range of immunoassay formats including, but not limited to, FLISA, Western Blot (WB). WB: 1:500-1:1000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the LIR1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Leukocyte Immunoglobulin-like Receptor 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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