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Immunohistochemistry (IHC) (Immunohistochemistry Analysis: Representative Lot Data. Paraffin-embedded colorectal adenocarcinoma (Fig. 1 & 2) tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:200 dilution of LAMP-3. Reactivity was detected using the IHC- Select® Detection Kit. Positive staining was observed in colorectal adenocarcinoma tissue.)

Mouse anti-Human LAMP3 Monoclonal Antibody | anti-LAMP3 antibody

LAMP3 (Lysosome-associated Membrane Glycoprotein 3, LAMP-3, Lysosomal-associated Membrane Protein 3, DC-lysosome-associated Membrane Glycoprotein, DC LAMP, Protein TSC403, CD208, DCLAMP, TSC403) (Biotin)

Gene Names
LAMP3; LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein G Affinity Chromatography
Synonyms
LAMP3; Monoclonal Antibody; LAMP3 (Lysosome-associated Membrane Glycoprotein 3; LAMP-3; Lysosomal-associated Membrane Protein 3; DC-lysosome-associated Membrane Glycoprotein; DC LAMP; Protein TSC403; CD208; DCLAMP; TSC403) (Biotin); anti-LAMP3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
13A205
Specificity
Recognizes human LAMP-3.
Purity/Purification
Purified by Protein G Affinity Chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-LAMP3 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Recombinant corresponding to human LAMP-3.
Conjugate
Biotin
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(Immunohistochemistry Analysis: Representative Lot Data. Paraffin-embedded colorectal adenocarcinoma (Fig. 1 & 2) tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:200 dilution of LAMP-3. Reactivity was detected using the IHC- Select® Detection Kit. Positive staining was observed in colorectal adenocarcinoma tissue.)

Immunohistochemistry (IHC) (Immunohistochemistry Analysis: Representative Lot Data. Paraffin-embedded colorectal adenocarcinoma (Fig. 1 & 2) tissue was prepared using heat-induced epitope retrieval in citrate buffer, pH 6.0. Immunostaining was performed using a 1:200 dilution of LAMP-3. Reactivity was detected using the IHC- Select® Detection Kit. Positive staining was observed in colorectal adenocarcinoma tissue.)

Western Blot (WB)

(Western Blotting Analysis: Representative Lot Data. MCF-7 cell lysate was probed with LAMP-3 (1ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and visualized using a chemiluminescence detection system. Arrow indicates LAMP-3 (~65kD).)

Western Blot (WB) (Western Blotting Analysis: Representative Lot Data. MCF-7 cell lysate was probed with LAMP-3 (1ug/ml). Proteins were visualized using a Goat Mouse IgG secondary antibody conjugated to HRP and visualized using a chemiluminescence detection system. Arrow indicates LAMP-3 (~65kD).)
Product Categories/Family for anti-LAMP3 antibody
References
1. Nagelkerke, A., et al. (2011). Cancer. doi: 10.1002/cncr.25938 {Published ahead of print} 2. Grutzkau, A., et al. (2004). Cytometry A. 61(1): 62-68. 3. de Saint-Vis, B., et al. (1998). Immunity. 9(3):325-336.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38.8kDa (362aa) 57-70KDa (SDS-PAGE under reducing conditions)
NCBI Official Full Name
lysosome-associated membrane glycoprotein 3
NCBI Official Synonym Full Names
lysosomal associated membrane protein 3
NCBI Official Symbol
LAMP3
NCBI Official Synonym Symbols
LAMP; CD208; DCLAMP; LAMP-3; TSC403; DC LAMP; DC-LAMP
NCBI Protein Information
lysosome-associated membrane glycoprotein 3
UniProt Protein Name
Lysosome-associated membrane glycoprotein 3
UniProt Gene Name
LAMP3
UniProt Synonym Gene Names
DCLAMP; TSC403; LAMP-3; Lysosomal-associated membrane protein 3; DC LAMP
UniProt Entry Name
LAMP3_HUMAN

NCBI Description

Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010]

Uniprot Description

LAMP3: Might change the lysosome function after the transfer of peptide-MHC class II molecules to the surface of dendritic cells. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q26.3-q27

Cellular Component: lysosomal membrane; integral to membrane

Biological Process: cell proliferation; immune system process

Research Articles on LAMP3

Similar Products

Product Notes

The LAMP3 lamp3 (Catalog #AAA6243060) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The LAMP3 (Lysosome-associated Membrane Glycoprotein 3, LAMP-3, Lysosomal-associated Membrane Protein 3, DC-lysosome-associated Membrane Glycoprotein, DC LAMP, Protein TSC403, CD208, DCLAMP, TSC403) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LAMP3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the LAMP3 lamp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMP3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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