Immunofluorescence/Immunocytochemistry (IF/ICC)
Mouse anti-Human, Mouse Lamin A Monoclonal Antibody | anti-lmna antibody
Mouse Anti-Lamin A [JOL4]
Gene Names
lmna; lmna-A
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Unpurified
Synonyms
Lamin A; Monoclonal Antibody; Mouse Anti-Lamin A [JOL4]; 70 kDa lamin antibody; CDCD1 antibody; CDDC antibody; CMD1A antibody; CMT2B1 antibody; EMD2antibody; FPL antibody; FPLD antibody; HGPS antibody; IDC antibody; LAMIN A antibody; lamin A/Cantibody; LAMIN C antibody; Lamin-A/C antibody; LDP1 antibody; LFP antibody; LGMD1B antibody; LMN 1antibody; LMN A antibody; LMN C antibody; LMN1 antibody; LMNA antibody; LMNA_HUMAN antibody; LMNC antibody; NYREN 32 antigen antibody; PRO1 antibody; Renal carcinoma antigen NY-REN-32 antibody; anti-lmna antibody
Host
Mouse
Reactivity
Human, Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
JOL4
Specificity
The antibody reacts with both recombinant and native lamin A in humans, binding to an epitope between amino acids 572-646
Purity/Purification
Unpurified
Form/Format
Tissue culture supernatant containing 0.2M Tris/HCl pH7.4 and 510% foetal calf serum;
Sequence Length
665
Applicable Applications for anti-lmna antibody
Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Optimal antibody dilution should be determined by titration, however as a guideline try; IP: Use neat. WB: 1/50. Predicted molecular weight: 74 kDa.
Target Antigen
Lamin A
Immunogen
Recombinant human lamin A
Myeloma/fusion Partners
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP20/Ag4 myeloma cell line;
Research Areas
Cell Biology; Class V Lamins; Cytoskeleton; Cytoskeleton / ECM; Intermediate Filaments; Lamins; Nuclear Envelope; Nucleus; Subcellular Markers; Tags Cell Markers
Immunofluorescence/Immunocytochemistry (IF/ICC)
Immunofluorescence/Immunocytochemistry (IF/ICC)
References
Both emerin and lamin C depend on lamin A for localization at the nuclear envelope. Vaughan A (J Cell Sci,Jul 2001)PUBMED
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,919 Da
NCBI Official Full Name
lamin-A
NCBI Official Synonym Full Names
lamin A/C<
NCBI Official Symbol
lmna
NCBI Official Synonym Symbols
lmna-A
NCBI Protein Information
lamin-A
UniProt Protein Name
Lamin-A
Protein Family
UniProt Gene Name
lmna
UniProt Entry Name
LMNA_XENLA
Uniprot Description
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Research Articles on lmna
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Product Notes
The lmna lmna (Catalog #AAA375037) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Lamin A [JOL4] reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Lamin A can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin, Immunoprecipitation (IP), Western Blot (WB). Optimal antibody dilution should be determined by titration, however as a guideline try; IP: Use neat. WB: 1/50. Predicted molecular weight: 74 kDa. Researchers should empirically determine the suitability of the lmna lmna for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lamin A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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