Mouse anti-Human LACC1 Monoclonal Antibody | anti-LACC1 antibody

LACC1 (Laccase Domain-containing Protein 1, C13orf31, DKFZp686D11119, FLJ38725, UPF0124 Protein) (Biotin)

Cat. Num. AAA6140875

• Gene Names: LACC1; FAMIN; C13orf31
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LACC1; Monoclonal Antibody; LACC1 (Laccase Domain-containing Protein 1; C13orf31; DKFZp686D11119; FLJ38725; UPF0124 Protein) (Biotin); anti-LACC1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG2b,k
• Clone Number: 2A1
• Specificity: Recognizes human C13orf31.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-LACC1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length recombinant protein corresponding to aa1-431 from human C13orf31 (AAH35749) with GST tag. MW of the GST tag alone is 26kD.
• Immunogen Sequence: MAEAVLIDLFGLKLNSQKNCHQTLLKTLNAVQYHHAAKAKFLCIMCCSNISYERDGEQDNCEIETSNGLSALLEEFEIVSCPSMAATLYTIKQKIDEKNLSSIKVIVPRHRKTLMKAFIDQLFTDVYNFEFEDLQVTFRGGLFKQSIEINVITAQELRGIQNEIETFLRSLPALRGKLTIITSSLIPDIFIHGFTTRTGGISYIPTLSSFNLFSSSKRRDPKVVVQENLRRLANAAGFNVEKFYRIKTHHSNDIWIMGRKEPDSYDGITTNQRGVTIAALGADCIPIVFADPVKKACGVAHAGWKGTLLGVAMATVNAMIAEYGCSLEDIVVVLGPSVGPCCFTLPRESAEAFHNLHPACVQLFDSPNPCIDIRKATRILLEQGGILPQNIQDQNQDLNLCTSCHPDKFFSHVRDGLNFGTQIGFISIKE
• Conjugate: Biotin
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot detection against Immunogen (73.41kD).)

Western Blot (WB)

(Western Blot analysis of C13orf31 expression in transfected 293T cell line by C13orf31 monoclonal antibody. Lane 1: C13orf31 transfected lysate (47.8kD). Lane 2: Non-transfected lysate.)

Testing Data

(Detection limit for recombinant GST tagged C13orf31 is 1ng/ml as a capture antibody.)

Product Categories/Family for anti-LACC1 antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 23242932
• NCBI GeneID: 144811
• Molecular Weight: 48KD
• NCBI Official Full Name: Homo sapiens chromosome 13 open reading frame 31, mRNA
• NCBI Official Synonym Full Names: laccase domain containing 1
• NCBI Official Symbol: LACC1
• NCBI Official Synonym Symbols: FAMIN; C13orf31
• NCBI Protein Information: laccase domain-containing protein 1
• Protein Family: Laccase domain-containing protein

NCBI Description

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]