Mouse anti-Human L-FABP Monoclonal Antibody | anti-FABP1 antibody

Anti-L-FABP Mouse mAb

Cat. Num. AAA475267

• Gene Names: FABP1; FABPL; L-FABP
• Reactivity: Human
• Applications: ELISA
• Purity: Affinity purified
• Synonyms: L-FABP; Monoclonal Antibody; Anti-L-FABP Mouse mAb; FABP 1; FABP1; FABPL; FABPL_HUMAN; Fatty Acid Binding Protein 1; Fatty acid binding protein 1 liver; Fatty Acid Binding Protein; Fatty acid-binding protein 1; Fatty acid-binding protein; Fatty acid-binding protein liver; L FABP; liver; Liver-type fatty acid-binding protein; anti-FABP1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: lgG1
• Clone Number: 8G6-D5
• Purity/Purification: Affinity purified
• Form/Format: PBS (pH 7.4) containing with 0.03% Proclin 300
• Concentration: 3.3mg/ml (varies by lot)
• Sequence Length: 127

• Applicable Applications for anti-FABP1 antibody: ELISA (EIA)
• Immunogen: Purified recombinant human L-FABP protein fragments expressed in E Coli.
• Entrez Summary: This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.

Standard Curve

(Standard Curve for L-FABP: Capture Antibody Mouse mAb (8G6-D5) to L-FABP and Detector Antibody Mouse mAb(2D6-F6) to L-FABP.)

Testing Data

(Observed L-FABP levels in several Human urine samples and Human serum samples at different dilution.)

Product Categories/Family for anti-FABP1 antibody

Signal Transduction; Metabolism; Lipid metabolism; Metabolism; Types of disease; Cancer

NCBI and Uniprot Product Information

• NCBI GI #: 4557577
• NCBI GeneID: 2168
• NCBI Accession #: NP_001434.1
• NCBI GenBank Nucleotide #: NM_001443
• UniProt Accession #: P07148
• Molecular Weight: 14
• NCBI Official Full Name: fatty acid-binding protein, liver
• NCBI Official Synonym Full Names: fatty acid binding protein 1
• NCBI Official Symbol: FABP1
• NCBI Official Synonym Symbols: FABPL; L-FABP
• NCBI Protein Information: fatty acid-binding protein, liver
• UniProt Protein Name: Fatty acid-binding protein, liver
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP1
• UniProt Synonym Gene Names: FABPL; L-FABP
• UniProt Entry Name: FABPL_HUMAN

NCBI Description

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

Uniprot Description

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: apical cortex; cytoplasm; cytosol; nucleoplasm; peroxisomal matrix

Molecular Function: antioxidant activity; bile acid binding; chromatin binding; drug binding; fatty acid binding; long-chain fatty acid transporter activity; phospholipid binding; protein binding

Biological Process: cellular lipid metabolic process; intestinal absorption; long-chain fatty acid transport; negative regulation of apoptosis; negative regulation of caspase activity; positive regulation of cell proliferation; positive regulation of defense response to virus by host; positive regulation of fatty acid beta-oxidation; positive regulation of hydrolase activity; triacylglycerol catabolic process