Western Blot (WB)
(Western blot analysis using KSHV ORF45 mouse mAb against KSHV ORF45 recombinant protein.)
Mouse KSHV ORF45 Monoclonal Antibody | anti-KSHV ORF45 antibody
Anti-KSHV ORF45 Mouse mAb
Reactivity
KSHV
Applications
Western Blot, Immunohistochemistry
Synonyms
KSHV ORF45; Monoclonal Antibody; Anti-KSHV ORF45 Mouse mAb; ORF45; anti-KSHV ORF45 antibody
Host
Mouse
Reactivity
KSHV
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2D4A5
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Applicable Applications for anti-KSHV ORF45 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Purified recombinant fragment of KSHV ORF45 expressed in E Coli.
Western Blot (WB)
(Western blot analysis using KSHV ORF45 mouse mAb against KSHV ORF45 recombinant protein.)
Western Blot (WB)
(Western blot analysis using KSHV ORF45 mouse mAb against KSHV ORF45 recombinant protein.)
Immunocytochemistry (ICC)
(ICC analysis of TPA induced BCBL-1 cells (A) and uninduced BCBL-1 cells (B) using KSHV ORF45 mouse mAb with AEC staining.)
Immunocytochemistry (ICC)
(ICC analysis of TPA induced BCBL-1 cells (A) and uninduced BCBL-1 cells (B) using KSHV ORF45 mouse mAb with AEC staining.)
Related Product Information for anti-KSHV ORF45 antibody
Entrez Summary: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus-mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus-induced production of type I IFN. Zhu et al (2003) reported that the ORF45 Protein was associated with purified virions
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Product Notes
The KSHV ORF45 (Catalog #AAA475650) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-KSHV ORF45 Mouse mAb reacts with KSHV and may cross-react with other species as described in the data sheet. AAA Biotech's KSHV ORF45 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the KSHV ORF45 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KSHV ORF45, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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