Western Blot (WB)
(Western blot analysis using KLHL22 mouse mAb against mouse brain tissues lysate.)
Mouse anti-Human KLHL22 Monoclonal Antibody | anti-KLHL22 antibody
Anti-KLHL22 Mouse mAb
Gene Names
KLHL22; KELCHL
Reactivity
Human
Applications
Western Blot, Immunocytochemistry
Synonyms
KLHL22; Monoclonal Antibody; Anti-KLHL22 Mouse mAb; KELCHL; anti-KLHL22 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
7B10
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
634
Applicable Applications for anti-KLHL22 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Purified recombinant fragment of human KLHL22 expressed in E Coli.
Western Blot (WB)
(Western blot analysis using KLHL22 mouse mAb against mouse brain tissues lysate.)
Western Blot (WB)
(Western blot analysis using KLHL22 mouse mAb against mouse brain tissues lysate.)
Immunofluorescence (IF)
(Immunofluorescence analysis of U251 cells using KLHL22 mouse mAb (green). Blue)
Immunofluorescence (IF)
(Immunofluorescence analysis of U251 cells using KLHL22 mouse mAb (green). Blue)
Related Product Information for anti-KLHL22 antibody
Entrez Summary: KLHL22 (kelch-like protein 22) is a 634 amino acid protein that is related to the Drosophilakelch protein, which is required to maintain Actin organization in ovarian ring canals. Mutations affecting Kelch function result in the failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL22 protein contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL22 that are produced as a result of alternative splicing events.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72
NCBI Official Full Name
kelch-like protein 22
NCBI Official Synonym Full Names
kelch like family member 22
NCBI Official Symbol
KLHL22
NCBI Official Synonym Symbols
KELCHL
NCBI Protein Information
kelch-like protein 22
UniProt Protein Name
Kelch-like protein 22
Protein Family
UniProt Gene Name
KLHL22
Uniprot Description
KLHL22: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for cell division. BCR E3 ubiquitin ligase complexes mediate the ubiquitination of target proteins.
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: centrosome; cytoplasm; polar microtubule
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: cell division; mitotic cell cycle spindle assembly checkpoint; mitotic sister chromatid segregation; protein monoubiquitination
Research Articles on KLHL22
Similar Products
Product Notes
The KLHL22 klhl22 (Catalog #AAA476075) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-KLHL22 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLHL22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the KLHL22 klhl22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLHL22, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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