Testing Data
(Staining of a Kinesin, Heavy Chain in a PtK1 cell (red). The cell is double labeled with antiserum to tubulin (green). The kinesin positive structures correspond to the intermediate compartment, a membrane system. EAAC1-immunoreactivity is present in granules of pyramidal neuron and nerve fibers. Note that EAAC1-immunoreactivity is exclusively neuronal and distinct from GFAP-positive glial elements.)
Mouse Kinesin, Heavy Chain Monoclonal Antibody | anti-Khc antibody
Kinesin, Heavy Chain
Gene Names
Khc; CG7765; DK; DKH; DmelCG7765; DmK; DmKHC; Dmkin; khc; KHC; KIF5A; kin; Kin; KIN; kinesin; l(2)k13219; l(2)k13314; l(2)W12; l(2R)W12; pgs
Reactivity
Bovine, Mammal
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry, immunoassay, Radioimmunoassay
Purity
PurifiedPurified
Synonyms
Kinesin; Heavy Chain; Monoclonal Antibody; Anti -Kinesin; anti-Khc antibody
Host
Mouse
Reactivity
Bovine, Mammal
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2Q80
Specificity
Recognizes the heavy chain of bovine kinesin near the N-terminus.
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.
Applicable Applications for anti-Khc antibody
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Radioimmunoassay (RIA)
Application Notes
Suitable for use in Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA, RIA and Immunoprecipitation.
Dilution: Immunohistochemistry: Paraformaldehyde fixed tissue. Also works for EM.
Dilution: Immunohistochemistry: Paraformaldehyde fixed tissue. Also works for EM.
Immunogen
Bovine brain kinesin
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(Staining of a Kinesin, Heavy Chain in a PtK1 cell (red). The cell is double labeled with antiserum to tubulin (green). The kinesin positive structures correspond to the intermediate compartment, a membrane system. EAAC1-immunoreactivity is present in granules of pyramidal neuron and nerve fibers. Note that EAAC1-immunoreactivity is exclusively neuronal and distinct from GFAP-positive glial elements.)
Testing Data
(Staining of a Kinesin, Heavy Chain in a PtK1 cell (red). The cell is double labeled with antiserum to tubulin (green). The kinesin positive structures correspond to the intermediate compartment, a membrane system. EAAC1-immunoreactivity is present in granules of pyramidal neuron and nerve fibers. Note that EAAC1-immunoreactivity is exclusively neuronal and distinct from GFAP-positive glial elements.)
Related Product Information for anti-Khc antibody
Kinesin belongs to the group of motor proteins known to convert chemical energy released from ATP into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport inneuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120-130kD) and two light chains (60-70kD), resulting in a molecular mass about 400kD. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function.
Product Categories/Family for anti-Khc antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
kinesin heavy chain
NCBI Official Synonym Full Names
Kinesin heavy chain
NCBI Official Symbol
Khc
NCBI Official Synonym Symbols
CG7765; DK; DKH; DmelCG7765; DmK; DmKHC; Dmkin; khc; KHC; KIF5A; kin; Kin; KIN; kinesin; l(2)k13219; l(2)k13314; l(2)W12; l(2R)W12; pgs
NCBI Protein Information
CG7765 gene product from transcript CG7765-RA; kinesin heavy chain; CG7765-PA; Khc-PA; kinesin alpha subunit; kinesin-1; kinesin alpha-chain; partagas; kinesin 1; kinesin I; kinesin-1 heavy chain; kinesin heavy chain I
Research Articles on Khc
Similar Products
Product Notes
The Khc (Catalog #AAA632380) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Kinesin, Heavy Chain reacts with Bovine, Mammal and may cross-react with other species as described in the data sheet. AAA Biotech's Kinesin, Heavy Chain can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Radioimmunoassay (RIA). Suitable for use in Immunohistochemistry, Immunocytochemistry, Western Blot, ELISA, RIA and Immunoprecipitation. Dilution: Immunohistochemistry: Paraformaldehyde fixed tissue. Also works for EM. Researchers should empirically determine the suitability of the Khc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kinesin, Heavy Chain, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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